Meptyldinocap - CAS 131-72-6
Catalog number: 131-72-6
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H24N2O6
Molecular Weight:
364.39
COA:
Inquire
Targets:
Others
Description:
Meptyldinocap (2,4-DNOPC) is a novel powdery mildew (Erysiphe necator) fungicide which shows protectant and post-infective activities.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
2,4-DNOPC
MSDS:
Inquire
1.Analytical method validation for the determination of meptyldinocap as 2,4-dinitrooctylphenol metabolite in mango and soil using LC-MS/MS and dissipation study of the fungicide in Indian mango field
Mandal S1, Kanrar B, Das S, Bhattacharyya A. J Agric Food Chem. 2010 Aug 25;58(16):8911-7. doi: 10.1021/jf1008346. Epub 2010 Jul 22.
An analytical method for the quantitative determination of meptyldinocap (2,4-DNOPC) as 2,4-dinitrooctylphenyl (2,4-DNOP) in mango and soil was developed as well as validated using liquid chromatography tandem mass spectrometry (LC-MS/MS). The method comprised an extraction with an acetone:methanol:4 N HCl (100:10:5, v/v/v) mixture followed by hydrolytic conversion of parent 2,4-DNOPC to the corresponding phenol metabolite (2,4-DNOP), and cleanup was done by liquid:liquid partition using ethyl acetate. Final quantitation was performed by LC-MS/MS of 2,4-DNOP with negative electrospray ionization using gradient elution. The method was validated at concentrations ranging from 0.025 to 2 μg/g, and the limit of quantification (LOQ) of meptyldinocap in mango and soil samples was 0.025 μg/g. The recovery of meptyldinocap from mango and soil sample was found to be 93-98% spiked at different levels with analyte, and the relative standard deviation for repeatability (RSD(r)) and reproducibility (RSD(R)) were acceptable (2-6%).
2.A simple spectrophotometric determination of meptyldinocap by its hydrolysis.
Kurup S1, Pillai AK. Acta Chim Slov. 2013;60(1):81-6.
A simple spectrophotometric method is proposed for the determination of meptyldinocap (2,4-dinitro-6-octylphenyl crotonate). The method is based on the hydrolysis of meptyldinocap by hydroxylamine solution in alkaline medium to give 2,4-dinitro-6-octylphenol (2,4-DNOP), having maximum absorption at 380 nm. The reaction is found to be instantaneous in presence of ethanol. Beer's law is valid over the concentration range of 1.2-13 microg mL(-1) with molar absorptivity and Sandell's sensitivity of 3.22 x 10(6) L mol(-1) cm(-1) and 0.0001 microg cm(-2) respectively. The limit of detection and quantification were 0.0892 and 0.2703 microg mL(-1), respectively. The tolerance limits of interfering ions are discussed. All variables were studied in order to optimize the reaction conditions. The validity of the method was checked by its simultaneous determination in fruits and water samples and the results were statistically compared with those of a reference method by applying the Student's t-test and F-test.
3.Application of the KeratinoSens™ assay for assessing the skin sensitization potential of agrochemical active ingredients and formulations.
Settivari RS1, Gehen SC2, Amado RA2, Visconti NR3, Boverhof DR3, Carney EW3. Regul Toxicol Pharmacol. 2015 Jul;72(2):350-60. doi: 10.1016/j.yrtph.2015.05.006. Epub 2015 May 14.
Assessment of skin sensitization potential is an important component of the safety evaluation process for agrochemical products. Recently, non-animal approaches including the KeratinoSens™ assay have been developed for predicting skin sensitization potential. Assessing the utility of the KeratinoSens™ assay for use with multi-component mixtures such as agrochemical formulations has not been previously evaluated and is a significant need. This study was undertaken to evaluate the KeratinoSens™ assay prediction potential for agrochemical formulations. The assay was conducted for 8 agrochemical active ingredients (AIs) including 3 sensitizers (acetochlor, meptyldinocap, triclopyr), 5 non-sensitizers (aminopyralid, clopyralid, florasulam, methoxyfenozide, oxyfluorfen) and 10 formulations for which in vivo sensitization data were available. The KeratinoSens™ correctly predicted the sensitization potential of all the AIs. For agrochemical formulations it was necessary to modify the standard assay procedure whereby the formulation was assumed to have a common molecular weight.
4.A fast, inexpensive, and safe method for residue analysis of meptyldinocap in different fruits by liquid chromatography/tandem mass spectrometry.
Banerjee K1, Dasgupta S, Jadhav MR, Naik DG, Ligon AP, Oulkar DP, Savant RH, Adsule PG. J AOAC Int. 2010 Nov-Dec;93(6):1957-64.
An analytical method is reported for residue analysis of the fungicide meptyldinocap in different fruit matrixes that involves extraction with ethyl acetate, hydrolysis of the residues with ethanolamine, and determination by LC/MS/MS. The method involves extraction of 10 g sample with 10 mL ethyl acetate; evaporation of the ethyl acetate phase to dryness, and subsequent hydrolysis of the residues to 4,6-dinitro-2-(1-methylheptyl) phenol on reaction with 1% ethanolamine. The pH of this hydrolyzed product was neutralized with formic acid and analyzed by LC/MS/MS. The hydrolysis reaction followed pseudo-first-order kinetics, and the reaction product was spectroscopically confirmed as 2-(1-methylheptyl)-4,6-dinitrophenol. The method offered > 80% recoveries at an LOQ of 10 ng/g for grape and mango, 25 ng/g for pomegranate with intralaboratory Horwitz ratio < 0.5, and measurement uncertainties < 10% at LOQ levels. Considering first-order rate kinetics, activation energy, enthalpy of activation, and entropy of activation varied as solvent > mango > grape > pomegranate.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 3615-24-5 Ramifenazone

Ramifenazone
(CAS: 3615-24-5)

Ramifenazone is a non-steroidal anti-inflammatory synthetic reagent.

Hoechst 33342 trihydrochloride
(CAS: 875756-97-1)

Hoechst 33342 trihydrochloride is a cell-permeable, benzimidazole dye that stains DNA by binding to the minor groove of adenine and thymine-rich sequences. It e...

ML192
(CAS: 460331-61-7)

ML192 is a selective ligands for GPR55 with 1080 nM potency for GPR55 and >45-fold antagonist and agonist selectivity against GPR35, CB1 and CB2.

CAS 915365-57-0 Cot inhibitor-1

Cot inhibitor-1
(CAS: 915365-57-0)

Cot inhibitor-1 is a COT/Tpl2 inhibitor.

CAS 143982-31-4 LY 186564

LY 186564
(CAS: 143982-31-4)

LY 186564 is a bio-active chemical,but no detailed information has been published yet.

CAS 175135-47-4 O4I1

O4I1
(CAS: 175135-47-4)

O4I1 is a potent inducer of Oct3/4. O4I1 enhanced Oct3/4 expression. O4I1 not only promoted expression and stabilization of Oct3/4 but also enhanced its transcr...

CAS 364779-15-7 Ginsenoside Rk3

Ginsenoside Rk3
(CAS: 364779-15-7)

Extract from the roots of Panax ginseng C. A. Mey often used as a major ingredient of the compound preparation for ischemic heart diseases. Ginsenoside Rk3 and ...

CAS 935467-97-3 TH-237A

TH-237A
(CAS: 935467-97-3)

TH-237A(meso-GS 164) is a novel neuroprotective agent exhibiting favorable permeation across the blood brain barrier.

CAS 125238-99-5 Fmoc-Dab(Boc)-OH

Fmoc-Dab(Boc)-OH
(CAS: 125238-99-5)

Fmoc-Dab(Boc)-OH is a useful building block for chemical synthesis

CAS 54350-48-0 Etretinate

Etretinate
(CAS: 54350-48-0)

Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.

CAS 125-69-9 Dextromethorphan hydrobromide

Dextromethorphan hydrobromide
(CAS: 125-69-9)

Non-competitive, low affinity NMDA receptor antagonist. Displays antitussive and neuroprotective effects. Active in vivo.

CAS 60166-93-0 Iopamidol

Iopamidol
(CAS: 60166-93-0)

Iopamidol is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco.

CAS 555-77-1 Trichlormethine

Trichlormethine
(CAS: 555-77-1)

Trichloromethane is a solvent, as a powerful blister agent used for chemical warfare.

CAS 1035979-44-2 P005672 HCl

P005672 HCl
(CAS: 1035979-44-2)

P005672 HCl is a novel, tetracycline-substituted, narrow-spectrum antibiotic compound used for treatment of bacterial infections and neoplasms. It is developed ...

CAS 135463-81-9 Coluracetam

Coluracetam
(CAS: 135463-81-9)

MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholin...

ALZ-801

ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer’s disease (AD). Compared to t...

CAS 938-73-8 2-Ethoxybenzamide

2-Ethoxybenzamide
(CAS: 938-73-8)

2-Ethoxybenzamide is a common analgesic and anti-inflammatory drug. It is used to reduce the fever, headaches, and other minor aches and pains. It is an ingredi...

CAS 79-55-0 1,2,2,6,6-Pentamethylpiperidine

1,2,2,6,6-Pentamethylpiperidine
(CAS: 79-55-0)

1,2,2,6,6-Pentamethylpiperidine is a ganglion-blocking drug. It is one of the most strongly basic tertiary amine. It is ued as an oral treatment for hypertensio...

AT-584
(CAS: 16810-17-6)

AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies.

CAS 41078-02-8 Enprofylline

Enprofylline
(CAS: 41078-02-8)

Enprofylline, a xanthine derivative, is a a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine rec...

Chemical Structure

CAS 131-72-6 Meptyldinocap

Quick Inquiry

Verification code

Featured Items