MEN11467 - CAS 214487-46-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C38H40N4O3
Molecular Weight:
600.75
COA:
Inquire
Targets:
Neurokinin Receptor
Description:
MEN11467, a pseudopeptide,is a new tachykinin NK1 receptor antagonist which potently antagonizes both tachykinin and antigen-mediated inflammatory responses of the respiratory tract 'in vivo’ and which possesses a nanomolar affinity for guinea-pig and human tachykinin NK receptors.
Publictions citing BOC Sciences Products
  • >> More
Synonyms:
N-[(1S,2R)-2-[[(2R)-2-[methyl-[2-(4-methylphenyl)acetyl]amino]-3-naphthalen-2-ylpropanoyl]amino]cyclohexyl]-1H-indole-3-carboxamide
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
926.8±65.0 ℃ at 760 Torr
Density:
1.26±0.1 g/cm3
InChIKey:
JXDKAWGCUBTYFX-BMPTZRATSA-N
InChI:
1S/C38H40N4O3/c1-25-15-17-26(18-16-25)23-36(43)42(2)35(22-27-19-20-28-9-3-4-10-29(28)21-27)38(45)41-34-14-8-7-13-33(34)40-37(44)31-24-39-32-12-6-5-11-30(31)32/h3-6,9-12,15-21,24,33-35,39H,7-8,13-14,22-23H2,1-2H3,(H,40,44)(H,41,45)/t33-,34+,35+/m0/s1
Canonical SMILES:
CC1=CC=C(C=C1)CC(=O)N(C)C(CC2=CC3=CC=CC=C3C=C2)C(=O)NC4CCCCC4NC(=O)C5=CNC6=CC=CC=C65
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Neurokinin Receptor Products


CAS 137593-52-3 GR 64349

GR 64349
(CAS: 137593-52-3)

GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon).

CAS 290297-26-6 Netupitant

Netupitant
(CAS: 290297-26-6)

Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity o...

CAS 86933-74-6 Neurokinin A

Neurokinin A
(CAS: 86933-74-6)

Neurokinin A is a member of the endogenous tachykinin agonist with preference for the NK-2R (NK-2 receptor).

CAS 214487-46-4 MEN11467

MEN11467
(CAS: 214487-46-4)

MEN11467, a pseudopeptide,is a new tachykinin NK1 receptor antagonist which potently antagonizes both tachykinin and antigen-mediated inflammatory responses of ...

CAS 97559-35-8 Neurokinin A(4-10)

Neurokinin A(4-10)
(CAS: 97559-35-8)

Neurokinin A (4-10), an endogenous neuromodulatory peptide formerly known as substance K, is atachykinin NK2 receptor agonist.

Talnetant hydrochloride
(CAS: 204519-66-4)

Talnetant is the hydrochloride salt of Talnetant. Talnetant, also called as SB 223412, is a selective, competitive, nonpeptide NK3 receptor antagonist and is in...

CAS 147116-67-4 Maropitant

Maropitant
(CAS: 147116-67-4)

CAS 148687-76-7 L-733,060 hydrochloride

L-733,060 hydrochloride
(CAS: 148687-76-7)

The hydrochloride salt form of L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ a...

CAS 148700-85-0 L-733,060

L-733,060
(CAS: 148700-85-0)

L-733,061, a phenylpiperidine derivative, has been found to be a NK1 receptor antagonist that could probably be antidepressant/ anxiolytic agent and also show a...

CAS 86933-75-7 Neurokinin B

Neurokinin B
(CAS: 86933-75-7)

Neurokinin B, one of the tachykinin family of peptides, binds a family of GPCRs—including neurokinin receptor 1 (NK1R), NK2R, and NK3R to mediate their biologic...

CAS 914462-92-3 Rolapitant HCl hydrate

Rolapitant HCl hydrate
(CAS: 914462-92-3)

Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unl...

CAS 2507-24-6 Physalaemin

Physalaemin
(CAS: 2507-24-6)

Physalaemin, a non-mammalian tachykinin originally isolated from the Physalaemus frog, binds selectively to neurokinin-1 (NK1) receptor with high affinity.

CAS 172673-20-0 Fosaprepitant dimeglumine

Fosaprepitant dimeglumine
(CAS: 172673-20-0)

CAS 122063-01-8 [bAla8]-Neurokinin A(4-10)

[bAla8]-Neurokinin A(4-10)
(CAS: 122063-01-8)

An agonist of neurokinin 2 (NK2) receptor

CAS 110880-55-2 [Sar9,Met(O2)11]-Substance P

[Sar9,Met(O2)11]-Substance P
(CAS: 110880-55-2)

A selective agonist of tachykinin NK1 receptor

CAS 63968-82-1 Kassinin

Kassinin
(CAS: 63968-82-1)

Kassinin, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signalling and shows selectivit...

CAS 170729-80-3 Aprepitant

Aprepitant
(CAS: 170729-80-3)

CAS 33507-63-0 Substance P

Substance P
(CAS: 33507-63-0)

Substance P, a neuropeptide, is a sensory neuropeptide and inflammatory mediator. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor...

Chemical Structure

CAS 214487-46-4 MEN11467

Quick Inquiry

Verification code

Featured Items