|Description||Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2.|
Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively ...
Medroxy Progesterone is an orally active progestogen used in hormone replacement therepy (HRT).
JNJ-1250132, a new steroidal progestin antagonist, inhibits binding of the receptor to DNA in vitro. JNJ-1250132 induces a receptor conformation more similar to...
Chlormadinone acetate, with antiandrogen and antiestrogenic activities it is a steroidal progestin used in combinations as an oral contraceptive.
Telapristone acetate, also known as CDB-4124, acts as an investigational selective progesterone receptor modulator (SPRM) tested for treatment of progesterone s...
Tanaproget is a novel nonsteroidal progesterone receptor agonist that is first in its class and has high affinity and selectivity for the progesterone receptor....
Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
Vilaprisan is a selective oral progesterone receptor antagonist under the development of Bayer HealthCare Pharmaceuticals. BAY 1002670 showed a marked dose-depe...
Norethindrone, a synthetic progestin, is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases (SULT).
Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent...
Desogestrel is a progestogen with low androgenic potency used in hormonal contraceptives..
Gestodene is a progestogen hormonal contraceptive.Gestodene is androgenically neutral, meaning that contraceptive pills containing gestodene do not exhibit the ...
Telapristone, the active metabolite of telapristone acetate (also known as CDB-4124), is a selective progesterone antagonist developed for the long-term treatme...
Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2.
CP-8668 is an orally active nonsteroidal progesterone receptor modulator with no significant affinity for human glucocorticoid receptor or human estrogen recept...
Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.
Ulipristal Acetate is an orally bioactive and selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. It binds to...
Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...
Progesterone, synthesized from cholesterol by the sequential action of desmolase in the mitochondria, plays an important role in brain function as a endogenous ...