|Description||Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.|
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes ...
Diclazuril is an anti-coccidial drug.
PPA-904 is a specific phenothiazine photosensitizer that reached a phase II trial in patients with chronic venous Leg ulcer but was subsequently discontinued.
GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=...
Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity.
Niclosamide Monohydrate is used for the treatment of most tapeworm infections by inhibiting DNA replication. It inhibits the TNF-induced NF-κB reporter activity...
Dinitolmide is a broad-spectrum anticoccidial drug.
RRX-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increas...
Ronidazole is an antiprotozoal agent.
Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.
Secnidazole (Flagentyl) is a nitroimidazole anti-infective.
3,5-Dinitrobenzamide is an anti-parasitic agent.
Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective aga...
Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazen...
Diethylcarbamazine Citrate can be used as an anthelmintic. The LD50 in rats is 1.38 g/kg.
Flubendazole is an anthelmintic agent for MDAY-D2 cells with IC50 of 3 nM. Its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N...
Oxyclozanide is a salicylanilide anthelmintic used in the treatment and control of Fascioliasis in ruminants mainly domestic animals like Cattle, Sheep and Goat...
N,N-Diethyl-3-methylbenzamide, a benzamide derivative, could be a significant additive in vermifuge.
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. It is a promising compound for the therapy and prophylaxis of a...
Ferroquine, a ferrocene-based analogue, is an ingenious antimalarial agent potentially for the treatment of malaria.