|Targets||4-1BB(also known as CD137)|
|Description||MEDI6469 is an agonistic monoclonal antibody that binds to and activates a protein in humans called OX40. Because OX40 helps activate the immune system, it is hoped that it has potential immunostimulatory and antineoplastic activities.|
|Brife Description||Anti-OX40 monoclonal antibody with potential immunostimulatory and antineoplastic activities.|
|Synonyms||An agonistic anti-CD134 monoclonal antibody MEDI6469|
|Current Developer||MedImmune; Providence Cancer Center|
MEDI6469 is an agonistic monoclonal antibody that binds to and activates a protein in humans called OX40. Because OX40 helps activate the immune system, it is h...
A fully humanized monoclonal antibody (mAb) that stimulates signaling through 4-1BB (CD-137), a protein expressed in many immune cells.
A fully human IgG4 monoclonal antibody developed for the treatment of cancer and solid tumors targets the CD137 receptor. It specifically binds to and activates...