|Description||Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.|
Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering ...
Guanfacine HCl is the hydrochloride salt of Guanfacine. Guanfacine, a selective agonist of α2A receptor, is a sympatholytic drug to treat attention deficit hype...
Yohimbine, an indolalkylamine alkaloid, blocks presynaptic alpha-2 adrenergic receptors. IC50= 0.6 μM Ki: 1.05 nM, alphaα2Areceptor
Metoprolol succinate is a selective β-adrenoceptor antagonist. It is used in treatment of several diseases of the cardiovascular system. It is a drug used in th...
Salbutamol is a short-acting agonist that specifically targets β2-adrenergic receptor to alleviate bronchospasm in conditions such as asthma and chronic obstruc...
Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.
CL 316243 disodium salt
The sodium salt form of CL 316243, which has been found to be a β3-adrenoceptor agonist and could probably decrease blood insulin as well as glucose levels.
Tertatolol, a benzothiopyran derivative, is a potent dual antagonist of beta-adrenoceptor and 5-HT receptor, with antihypertensive effect.
L-748,337 is a selective and competitive β3-adrenoceptor antagonist with Ki value of 4.0 nM. It can inhibit agonist-induced relaxation of smooth muscle and lipo...
(R)-(-)-Niguldipine Hydrochloride, the less active enantiomer of Niguldipine Hydrochloride, is an L-type calcium channel protein inhibitor and α1A-AR (α1A-adren...
Nolomirole is a Alpha 2 adrenergic receptor and Dopamine D2 receptor agonist. Nolomirole can attenuate the heart failure signs in the monocrotaline-induced cong...
Carteolol HCl is a β-adrenoceptor antagonist, used for the treatment of glaucoma.
SDZ 21009 is a β-adrenoceptor and 5-HT1A/1B receptor antagonist (pKB/pA2 = 8.3 and 8.0 for 5-HT1A and 5-HT1B receptors, respectively).
Practolol is a selective beta-1 adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. lt competes with adrenergic neurotra...
CHIR 2279, an isoquinolin derivative, was once studied against hypertension as an α1 adrenergic receptor antagonist.
A 61603 hydrobromide
A 61603 hydrobromide is a potent and selective α-adrenoceptor agonist with 35-fold selectivity for α1A over α1B or α1D sites. Activation of the α1A-adrenergic r...
Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM, used as a "reliever" inhaler in the management of asthma symptoms and as a...
Levobunolol hydrochloride, a beta1- and beta2-adregergic blocking agent, has proved to be an effective ocular hypotensive agent to treat glaucoma.
Formoterol Hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with pKd of 8.12 and 5.58, respectively.