|Description||Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.|
ABT-866 is a novel alpha-adrenoceptor agent that demonstrates intrinsic activity at the α1A-adrenoceptor subtype present in the rabbit urethra (pD2=6.22, with 8...
Solabegron hydrochloride is a selective β3-adrenergic receptor agonist used for the treatment of irritable bowel syndrome.
Midodrine is a Alpha adrenergic receptor under the development of Shire for the treatment of dysautonomia and orthostatic hypotension. In August 2010, the FDA p...
Tamsulosin could block on the sympathetic α1 receptor, especially selectively bind to the α1A receptor and has been found to be effective in the treatment of be...
(R,R)-Formoterol is a long acting beta-adrenoceptor agonist acts as a novel highly β2-selective adrenergic agonist and holds promise as a β2-agonist that could ...
SynephrineHCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.
Fenspiride is an α adrenergic and H1 histamine receptor antagonist. It is an oxazolidinone spiro compound. It is used as a drug in the treatment of certain resp...
Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
DG5128, a new oral hypoglycemic agent, is an orally available preferential antagonist of α2-adrenoceptor with 7.4 times higher affinity toward α2-adrenoceptor t...
Propranolol hydrochloride, with antihypertensive, antianginal and antiarrhythmic (class II) properties, is a non-cardioselective adrenergic-beta antagonist and ...
Bambuterol is a long acting beta-adrenoceptor agonist (LABA) and is used in the treatment of asthma. It is an ester prodrug of the ß2-adrenergic agonist terbuta...
D2343 is a dual inhibitor of β2-adrenoceptor and α1- adrenoceptor. Inhaled D2343 has a longer bronchodilating effect than terbutaline.
Hoku 81 is a bronchodilator, and one of the metabolites of tulobuterol.
Propranolol Hydrochloride is a β-adrenergic antagonist used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary h...
MK-351 hydrochloride is an alpha-adrenergic agonist selective for α2-adrenergic receptors. It is a psychoactive drug used as a sympatholytic or antihypertensive...
Oxymetazoline, an imidazol derivative, has been found to be an adrenergic receptor agonist that could be an effective topical decongestant.
Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.
Nolomirole is a Alpha 2 adrenergic receptor and Dopamine D2 receptor agonist. Nolomirole can attenuate the heart failure signs in the monocrotaline-induced cong...
Medetomidine is a potent, highly selective α2-adrenoceptor agonist, which Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively. It is often ...
ICI 118551 hydrochloride
ICI 118551 hydrochloride is a highly selective β2 adrenergic antagonist (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively), inhibited ...