Meclinertant - CAS 146362-70-1
Catalog number:
146362-70-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C32H31ClN4O5
Molecular Weight:
587.07
COA:
Inquire
Targets:
Neurotensin Receptor
Description:
Meclinertant, a chloroquinolin derivative, has been found to be a Neurotensin receptor antagonist that could be probably effective against schizophrenia and some sorts of drug addiction at some extent. It has been already discontinued by sanofi-aventis for Small cell lung cancer. IC50: 15.3 and 20.4 nM for NTS1 and NTS2 respectively.
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Purity:
98%
Appearance:
Powder
Synonyms:
Meclinertant; SR 48692; SR-48692; Reminertant; SR48692
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
DYLJVOXRWLXDIG-UHFFFAOYSA-N
InChI:
InChI=1S/C32H31ClN4O5/c1-41-27-4-3-5-28(42-2)29(27)26-16-24(36-37(26)25-8-9-34-23-15-21(33)6-7-22(23)25)30(38)35-32(31(39)40)19-11-17-10-18(13-19)14-20(32)12-17/h3-9,15-20H,10-14H2,1-2H3,(H,35,38)(H,39,40)
Canonical SMILES:
COC1=C(C(=CC=C1)OC)C2=CC(=NN2C3=C4C=CC(=CC4=NC=C3)Cl)C(=O)NC5(C6CC7CC(C6)CC5C7)C(=O)O
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CAS 146362-70-1 Meclinertant

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