|Description||Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin|
|Purity||95 % (NMR).|
|Solubility||well in alcohol and water.|
|Storage||store at room temperature.|
|Melting Point||249-250 °C.|
Methimazole inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous ...
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Tschimgine a substance presenting an estrogenic activity..
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
A SR-4 agonist with moderate activity as a SR-3 antagonist
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium c...
Alkaloid , from plants of the Ungernia genus, Amaryllidaceae.
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Diamine oxidase activator. Na+ channels blocker.
Ca2+-Activated K+ Channel Blocker
Bicyclic diterpenoid of the clerodane series
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.