|Description||Benzimidazole antihelmintic. Tubulin-disrupting drug. Antitumour activity in vitro and in vivo. Inhibits growth and induces apoptosis.|
Ivermectin is a broad-spectrum antiparasitic medication.
Oxantel Pamoate is used as an anthelmintic. It has typically been used human and animal use as a standard treatment for intestinal worms. lt may be used as a fu...
Tetramisole is a mixture of dextro- and levo isomers used as an anthelmintic.
GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=...
Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagil...
Azithromycin is marginally less active than erythromycin in vitro against Gram-positive organisms, although this is of doubtful clinical significance as suscept...
Nimorazole is a nitroimidazole anti-infective. It significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be...
Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as ...
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.
Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazen...
Fenchlorphos, with high toxicity it is an organophosphorus pesticide to prevent and cure the parasitic in veterinary medicine.
Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity.
NITD609 is a novel antimalarial drug candidate, with IC50 of appr 1 nM against P. falciparum.
Bithionol is a clinically approved anti-parasitic drug. It has been shown to inhibit solid tumor growth in several preclinical cancer models. It caused dose dep...
N,N-Diethyl-3-methylbenzamide, a benzamide derivative, could be a significant additive in vermifuge.
Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites. It, sold by the Bayer Corporation under the trade name Marquis, is a drug curre...
DB289 (pafuramidine maleate; 2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) is a prodrug of DB75 (furamidine dihydrochloride; 2,5-bis(4-guanylphenyl)fura...
Permethrin is a synthetic pyrethroid insectide, affecting neuron membranes by prolonging sodium channel activation.
Naftalofos, an isoquinolin derivative, has been found to be an insecticide and commonly used in sheep.
Morantel tartrate, the 3-methyl thiophene tartrate salt analog of pyrantel tartrate, is a low toxic broad spectrum anthelmintic that is effective against the im...