|Description||(±)-MDL 105725 is an active metabolite of MDL 100907, which is a 5-HT2A receptor antagonist.|
|Brife Description||5-HT2A receptor antagonist|
Setiptiline maleate is a serotonin receptor antagonist. It is used as a tetracyclic antidepressant (TeCA) and acts as a noradrenergic and specific serotonergic ...
VUF 10166 is a potent and competitive 5-HT3 receptor antagonist (IC50 = 0.04 and 22 nM for human 5HT3A and 5-HT3AB receptors, respectively). VUF 10166 exhibits ...
Naronapride is a selective 5-HT(4) receptor agonist for gastrointestinal motility disorders. It can accelerate overall colonic transit and tend to accelerate GE...
Nelotanser is Serotonin 2A receptor inverse agonist. In Aug 2016, Axovant Sciences initiated a phase-II clinical trial in Lewy body disease in USA.
Pizotifen, also called as BC 105, a benzocycloheptathiophene derivative that is a highly selective 5-HT receptor blocking agent both in vivo (on saphenous veins...
SB 221284 is a potent and selective 5-HT2C/2B receptor antagonist (pKi = 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors, respectively).
GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...
N-Methylquipazine dimaleate, a tertiary amine analog of quipazine, is a 5-HT3 agonist, which has almost the same affinity for 5-HT3 sites as quipazine but unlik...