(±)-McN 5652 - CAS 96795-89-0
Category: Inhibitor
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Molecular Formula:
C19H21NS
Molecular Weight:
295.44
COA:
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Targets:
5-HT Receptor
Description:
(±)-McN 5652 is a potent, orally active 5-HT uptake inhibitor. McN-5652 is characterized by exceptionally high potency as an inhibitor of the uptake of serotonin by rat brain synaptosomes in vitro (Ki approximately 0.6 nM) and ex vivo (ED50 approximately 2 mg/kg p.o.). (±)-McN 5652 is a potent, selective inhibitor of serotonin reuptake in mammalian brain. It potently potentiates 5-HT-induced effects in vivo following oral administration. Its biological activity resides predominantly in the (+)-enantiomer.
Purity:
≥98% by HPLC
Synonyms:
(±)-McN 5652; (±)-McN5652; (±)-McN-5652; (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
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InChIKey:
YVKDUIAAPBKHMJ-MOPGFXCFSA-N
InChI:
InChI=1S/C19H21NS/c1-21-15-10-8-14(9-11-15)18-13-20-12-4-7-19(20)17-6-3-2-5-16(17)18/h2-3,5-6,8-11,18-19H,4,7,12-13H2,1H3
Canonical SMILES:
CSC1=CC=C(C=C1)C2CN3CCCC3C4=CC=CC=C24
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CAS 96795-89-0 (±)-McN 5652

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