MC 1742 - CAS 1776116-74-5
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C21H21N3O3S
Molecular Weight:
395.47
COA:
Inquire
Targets:
HDAC
Description:
MC 1742 is a novel and selective HDAC inhibitor with potential anticancer activity (IC50= 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 and HDAC8, respectively). Histone deacetylase inhibitor has been shown to induce growth arrest, apoptosis and differentiation in sarcoma cancer stem cells.
Purity:
≥98% by HPLC
Synonyms:
MC-1742; MC 1742; MC1742; 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
AOFVDNFTELWRHV-UHFFFAOYSA-N
InChI:
InChI=1S/C21H21N3O3S/c25-19(24-27)8-4-5-13-28-21-22-18(14-20(26)23-21)17-11-9-16(10-12-17)15-6-2-1-3-7-15/h1-3,6-7,9-12,14,27H,4-5,8,13H2,(H,24,25)(H,22,23,26)
Canonical SMILES:
C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC(=O)N=C(N3)SCCCCC(=O)NO
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related HDAC Products


CAS 1776116-74-5 MC 1742

MC 1742
(CAS: 1776116-74-5)

MC 1742 is a novel and selective HDAC inhibitor with potential anticancer activity (IC50= 7, 20, 40, 100, 110 and 610 nM for HDAC6, HDAC3, HDAC10, HDAC1, HDAC2 ...

CAS 1403783-31-2 Nexturastat A

Nexturastat A
(CAS: 1403783-31-2)

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM). Nextura...

CAS 156-54-7 Sodium butyrate

Sodium butyrate
(CAS: 156-54-7)

Sodium butyrate is the sodium salt of butyric acid, used in the culture of mammalian cells.

CAS 99-66-1 Valproic acid

Valproic acid
(CAS: 99-66-1)

Valproic acid is an inhibitor of histone deacetylase (HDAC) inhibitor, which has an anticancer effect. It is a branched short-chain fatty acid. It is previously...

CAS 852475-26-4 MC1568

MC1568
(CAS: 852475-26-4)

CAS 1045792-66-2 CAY10603

CAY10603
(CAS: 1045792-66-2)

CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respecti...

CAS 1418033-25-6 LMK-235

LMK-235
(CAS: 1418033-25-6)

LMK-235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor. LMK-235 demonstrates activity against chemoresistant cancer cell lines in an MTT assa...

CAS 3565-26-2 NSC 3852

NSC 3852
(CAS: 3565-26-2)

NSC 3852 is a histone deacetylase inhibitor. It is shown to have cell differentiation and antiproliferative activity in human breast cancer cells.

Chemical Structure

CAS 1776116-74-5 MC 1742

Quick Inquiry

Verification code

Featured Items