Maropitant - CAS 147116-67-4
Catalog number: 147116-67-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Neurokinin Receptor
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white solid powder
Maropitant; CJ-11972; CJ-11,972; CJ11,972. Cerenia
1.Evaluation of the antiemetic efficacy of maropitant in dogs medicated with morphine and acepromazine.
Lorenzutti AM1, Martín-Flores M2, Litterio NJ1, Himelfarb MA1, Zarazaga MP1. Vet Anaesth Analg. 2016 Mar;43(2):195-8. doi: 10.1111/vaa.12286. Epub 2015 Jun 19.
OBJECTIVE: To evaluate whether maropitant (1 mg kg(-1) ) injected subcutaneously (SC), administered simultaneously or 30 minutes prior to intramuscular (IM) administration of morphine (0.5 mg kg(-1) ) and acepromazine (0.05 mg kg(-1) ), reduces the incidence of salivation, retching and emesis in dogs.
2.Effects of the neurokinin-1 antagonist maropitant on canine gastric emptying assessed by radioscintigraphy and breath test.
Schmitz S1, Fink T, Failing K, Borsch C, Kunz C, Clemence R, Savary-Bataille K, Neiger R. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2016 Apr 19;44(3). [Epub ahead of print]
OBJECTIVE: Delayed gastric emptying is a well-recognised phenomenon in a number of canine disease conditions. Only a limited number of drugs have been reported to have some gastrokinetic effect in the dog. The aim of this study was to investigate prokinetic effects of maropitant.
3.Comparison of NK-1 Receptor Antagonist (Maropitant) to Morphine as a Pre-Anaesthetic Agent for Canine Ovariohysterectomy.
Marquez M1, Boscan P1, Weir H1, Vogel P1, Twedt DC1. PLoS One. 2015 Oct 29;10(10):e0140734. doi: 10.1371/journal.pone.0140734. eCollection 2015.
OBJECTIVE: To compare the NK-1 receptor antagonist maropitant to morphine during and after surgery in dogs undergoing ovariohysterectomy (OHE).
4.Evaluation of oral maropitant as an antiemetic in cats receiving morphine and dexmedetomidine.
Martin-Flores M1, Sakai DM2, Mastrocco A2, Learn MM2, Campoy L2, Kirch PJ2, Boesch JM2, Gleed RD2. J Feline Med Surg. 2015 Nov 3. pii: 1098612X15613389. [Epub ahead of print]
OBJECTIVES: The aim of the study was to evaluate the antiemetic effects of maropitant, after oral administration, in cats receiving morphine and dexmedetomidine.
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