Marinopyrrole A - CAS 1227962-62-0
Catalog number:
1227962-62-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H12Cl4N2O4
Molecular Weight:
510.15
COA:
Inquire
Targets:
Bcl-2 Family
Description:
Marinopyrrole A, a new Mcl-1 inhibitor, could influence Mcl-1-Bim interaction and induce the degradation of Mcl-1 proteasomal and also lead to the apoptosis of Mcl-1-dependent cancer cells. IC50: 10.1 uM.
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Purity:
95%
Appearance:
Powder
Synonyms:
Maritoclax; (±)-Marinopyrrole A
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
Marinopyrrole A is a new Mcl-1 inhibitor and could influence Mcl-1-Bim interaction and induce the degradation of Mcl-1 proteasomal and also lead to the apoptosis of Mcl-1-dependent cancer cells.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
QYPJBTMRYKRTFG-UHFFFAOYSA-N
InChI:
InChI=1S/C22H12Cl4N2O4/c23-12-9-13(19(31)10-5-1-3-7-14(10)29)28(22(12)26)18-16(24)21(25)27-17(18)20(32)11-6-2-4-8-15(11)30/h1-9,27,29-30H
Canonical SMILES:
OC1=CC=CC=C1C(C2=C(N3C(C(C4=CC=CC=C4O)=O)=CC(Cl)=C3Cl)C(Cl)=C(Cl)N2)=O
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