|Description||MAP4 is a selective group III metabotropic glutamate receptor (mGluR) antagonist in some electrophysiological systems. It acts as a group II/group III agonist in certain neurochemical systems. It modulates transmission of gustatory inputs in the brain system. It has displayed its potency in the perforant path of rat hippocampal slices.|
|Purity||≥96% by HPLC|
|Synonyms||(S)-2-Amino-2-methyl-4-phosphonobutyric acid; α-Methyl-AP4; MAP-4; MAP 4|
(RS)-3,5-DHPG is a group I metabotropic glutamate receptor (mGluR) agonist with selectivity for both mGlu1 and mGlu5. It is also acts as an antagonist at metabo...
O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of L-carnitine that transports fatty acids into the mitochondria. It was demonstrated that exhibits a...
(±)-ADX 71743 has been found to be a negative allosteric modulator at mGlu7 and is brain penetrant.
CPCCOEt has been found to be a mGluR-1 antagonist.
(RS)-MCPG Disodium Salt
(RS)-MCPG disodium salt is a non-selective group I/II metabotropic glutamate receptor antagonist.
Spaglumic acid is the most abundant peptide neurotransmitter in the mammalian CNS. Spaglumic acid is a weak activator of NMDA receptors and a highly selective a...
VU 0285683 is a negative allosteric modulator of mGlu5 receptors with high affinity for the MPEP binding site. VU 0285683 exhibits anxiolytic activity in rodent...
LY 379268 is a group II mGlu receptor agonist with EC50 values of 2.69 and 4.48 nM for hmGlu2 and hmGlu3. Some research shows that LY379268 can attenuate cocain...