Mafenide Acetate - CAS 13009-99-9
Catalog number:
13009-99-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C9H14N2O4S
Molecular Weight:
246.28
COA:
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Targets:
Antibacterial
Description:
Mafenide is a bacteriostatic antibiotic with a broad activity against Gram positive, Gram negative bacteria and Clostridia. Mafenide acetate penetrates eschar and prevents heavy colonization in burn wounds.
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Purity:
>98%
Synonyms:
Sulfamylon Acetate
MSDS:
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1.Evaluation of the Antimicrobial Effect of Chitosan/Polyvinyl Alcohol Electrospun Nanofibers Containing Mafenide Acetate.
Abbaspour M1, Sharif Makhmalzadeh B1, Rezaee B1, Shoja S2, Ahangari Z3. Jundishapur J Microbiol. 2015 Oct 28;8(10):e24239. doi: 10.5812/jjm.24239. eCollection 2015.
BACKGROUND: Chitosan, an important biodegradable and biocompatible polymer, has demonstrated wound-healing and antimicrobial properties.
2.The presence of soluble carbonic anhydrase in the thylakoid lumen of chloroplasts from Arabidopsis leaves.
Fedorchuk T1, Rudenko N2, Ignatova L1, Ivanov B1. J Plant Physiol. 2014 Jul 1;171(11):903-6. doi: 10.1016/j.jplph.2014.02.009. Epub 2014 Mar 11.
Supernatant obtained after high-speed centrifugation of disrupted thylakoids that had been washed free from extrathylakoid carbonic anhydrases demonstrated carbonic anhydrase activity that was inhibited by the specific inhibitors acetazolamide and ethoxyzolamide. A distinctive feature of the effect of Triton X-100 on this activity also suggested that the source of the activity is a soluble protein. Native electrophoresis of a preparation obtained using chromatography with agarose/mafenide as an affinity sorbent revealed one protein band with carbonic anhydrase activity. The same protein was revealed in a mutant deficient in soluble stromal carbonic anhydrase β-CA1, and this indicated that the newly revealed carbonic anhydrase is not a product of the At3g01500 gene. These data imply the presence of soluble carbonic anhydrase in the thylakoid lumen of higher plants.
3.Effect of Olea ointment and Acetate Mafenide on burn wounds - A randomized clinical trial.
Zahmatkesh M1, Manesh MJ2, Babashahabi R3. Iran J Nurs Midwifery Res. 2015 Sep-Oct;20(5):599-603. doi: 10.4103/1735-9066.164507.
BACKGROUND: The main goals in treating burns are to accelerate tissue renovation and prevent infection. Topical antibiotics are used in the treatment of burns, but they can cause side effects. Recently, a traditional ointment (Olea) has been used in Iran in the treatment of burns. This study examines the effect of topical honey ointment in healing of burn patients.
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CAS 13009-99-9 Mafenide Acetate

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