|Description||Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 by binding to the ATP-binding site.IC50 = 2μM. Exhibits antitumor and cytocidal activities (IC50~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Exhibits higher affinity and potency than geldanamycin.|
|Brife Description||Macbecin I is a Hsp90 inhibitor.|
|Appearance||Yellow lyophilised solid|
|Solubility||Soluble in DMSO|
|Storage||Desiccate at -20°C|
MPC-0767 is a novel L-alanine ester pro-drug of MPC-3100, designed to have improved aqueous solubility compared to MPC-3100.
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Nanoparticle albumin-bound 17-AAG
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