M-110 - CAS 1395048-49-3
Catalog number:
1395048-49-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H28ClN5O3
Molecular Weight:
445.95
COA:
Inquire
Targets:
Pim
Description:
M-110, a PIM kinases inhibitor, has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of Wnt/β-catenin. IC50: 0.6 to 0.9 uM.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
M-110; SCHEMBL16410885; SCHEMBL17821539; N'-[(1E)-1-(4-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)propyl]-2-(3-morpholin-4-ylpropylamino)pyridine-4-carbohydrazide
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
M-110 is a PIM kinases inhibitor that has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of Wnt/β-catenin.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Millgrams-Grams
InChIKey:
DSGHDBWWBOPZQP-VHEBQXMUSA-N
InChI:
InChI=1S/C22H28ClN5O3/c1-2-19(18-5-4-17(23)15-20(18)29)26-27-22(30)16-6-8-25-21(14-16)24-7-3-9-28-10-12-31-13-11-28/h4-6,8,14-15,26H,2-3,7,9-13H2,1H3,(H,24,25)(H,27,30)/b19-18+
Canonical SMILES:
CCC(=C1C=CC(=CC1=O)Cl)NNC(=O)C2=CC(=NC=C2)NCCCN3CCOCC3
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Pim Products


CAS 1204144-28-4 AZD-1208

AZD-1208
(CAS: 1204144-28-4)

AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity. AZD1208 inhibits the activities of PIM1, PIM2 and P...

Tp3654
(CAS: 1361951-15-6)

Tp3654 is an inhibitor of Pim-1 and Pim-3 that has the potential to treat prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis.

CX-6258 hydrochloride hydrate
(CAS: 1353858-99-7)

The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumor...

CAS 1202916-90-2 CX-6258

CX-6258
(CAS: 1202916-90-2)

LGB-321 HCl
(CAS: 1210416-93-5)

This active molecular is a selective ATP-competitive inhibitor of Pan-PIM kinase. LGB-321 is active in PIM2 dependent cell lines that is quite different to othe...

GDC-0339
(CAS: 1428569-85-0)

GDC-0339, also called as SCHEMBL14801965, is a selective inhibitor of BaF3 PIM1 that has the potential for treatment of cancer. BaF3 PIM1: IC50= 43.6 nM; PIM1 L...

M-110
(CAS: 1395048-49-3)

M-110, a PIM kinases inhibitor, has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of Wnt/β-catenin. IC...

CAS 491871-58-0 TCS PIM-1 1

TCS PIM-1 1
(CAS: 491871-58-0)

PIM447
(CAS: 1210608-43-7)

This active molecular is a potent PIM 1, 2, and 3 kinase inhibitor under the development of Novartis. In vivo, PIM447 reduces the tumor burden and also prevente...

CAS 1025065-69-3 SGI-1776

SGI-1776
(CAS: 1025065-69-3)

SGI-1776 is a small-molecule pan-Pim protein kinase inhibitor with potential antineoplastic activity. Pim kinase inhibitor SGI-1776 binds to and inhibits the ac...

CAS 438190-29-5 SMI 4a

SMI 4a
(CAS: 438190-29-5)

CAS 1093222-27-5 LKB1/AAK1 dual inhibitor

LKB1/AAK1 dual inhibitor
(CAS: 1093222-27-5)

LKB1/AAK1 dual inhibitor is an effective inhitor against multi-kinase especially Pim-1 kinase, which has been newly found to highly expressed in sorts of isolat...

CAS 587852-28-6 SMI-16a

SMI-16a
(CAS: 587852-28-6)

SMI-16a, a cell-permeable thiazolidinedione compound, is a selective and ATP-competitive Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1,...

CAS 2088852-47-3 PIM inhibitor 1 phosphate

PIM inhibitor 1 phosphate
(CAS: 2088852-47-3)

PAK4-IN-1 is an inhibitor of Pim (IC50< 35 nM).

SMI-4a
(CAS: 327033-36-3)

SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM aga...

Quick Inquiry

Verification code

Featured Items