|Description||Lys01 trihydrochloride, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth.|
|Brife Description||A novel lysosomal autophagy inhibitor|
|Synonyms||N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine;trihydrochloride; Lys01 (trihydrochloride)|
|Solubility||H2O: 6.4 mg/mL (Need ultrasonic)|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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Tyrosine kinase inhibitor
It is a Tyrosine kinase inhibitor.
AMG 337 is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor AMG 337 selectively binds to c-M...
Lys01 trihydrochloride, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respec...