Lys01 trihydrochloride - CAS 1391426-24-6
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H26Cl5N5
Molecular Weight:
549.75
COA:
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Targets:
c-Met/HGFR
Description:
Lys01 trihydrochloride, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth.
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Brife Description:
A novel lysosomal autophagy inhibitor
Synonyms:
N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine;trihydrochloride; Lys01 (trihydrochloride)
Solubility:
H2O: 6.4 mg/mL (Need ultrasonic)
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
JTUYDBHQGOZPQQ-UHFFFAOYSA-N
InChI:
1S/C23H23Cl2N5.3ClH/c1-30(12-10-28-20-6-8-26-22-14-16(24)2-4-18(20)22)13-11-29-21-7-9-27-23-15-17(25)3-5-19(21)23;;;/h2-9,14-15H,10-13H2,1H3,(H,26,28)(H,27,29);3*1H
Canonical SMILES:
CN(CCNC1=C2C=CC(=CC2=NC=C1)Cl)CCNC3=C4C=CC(=CC4=NC=C3)Cl.Cl.Cl.Cl
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CAS 1391426-24-6 Lys01 trihydrochloride

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