|Description||LY2334737 is an orally available valproic acid ester of gemcitabine, which is a broad-spectrum antimetabolite with antineoplastic activity. It is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy. It is hydrolyzed by carboxylesterase 2 (CES2) and releases gemcitabine systemically over a period of time consistent with formation rate-limited kinetics. It was less cytotoxic to a SK-OV-3 CES2 knockdown than parental cells.|
|Solubility||10 mM in DMSO|
|Application||LY2334737 is used as chemotherapy. It has antineoplastic activity.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Density||1.41±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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