|Description||LY 56110, a Pyrimidine derivative, is a novel class of nonsteroidal aromatase inhibitor. LY 56110 inhibited ethinamate-induced sleeping time in rats in vivo.|
|Synonyms||5-[bis(4-chlorophenyl)methyl]pyrimidine; LY 56110; LY-56110; LY56110|
YM 511 is a potent aromatase (CYP19) inhibitor (IC50 = 0.4 and 0.12 nM at rat ovary and human placenta cells, respectively) that weakly inhibits the synthesis o...
FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast c...
Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active.
Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported.
ORG 30958 is a potent aromatase inhibitor in vivo. ORG 30958 proved to be devoid of antiestrogenic activity which indicates that the absence of cornification of...
Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
LY 43578 is an aromatase inhibitor.
This active molecular has a potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits P450-dependent ATRA-4-hy...