|Description||LY 43578 is an aromatase inhibitor.|
|Appearance||Dark purple crystals or crystalline powder|
|Synonyms||bis(4-chlorophenyl)-pyrimidin-5-ylmethanol; LY 43578; LY 43578; LY 43578|
|Boiling Point||649.8ºC at 760 mmHg|
This active molecular has a potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits P450-dependent ATRA-4-hy...
Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
Cgp 47645 is non-steroidal aromatase inhibitor with anti-tumor and endocrine effects. It is orally active.
LY 56110, a Pyrimidine derivative, is a novel class of nonsteroidal aromatase inhibitor. LY 56110 inhibited ethinamate-induced sleeping time in rats in vivo.
Aminoglutethimide is an anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the ...
Cgp 45688 is an non-steroidal aromatase inhibitor originated byNovartis. It has anti-tumor effects, but no development for treatment of cancer was reported.
YM 511 is a potent aromatase (CYP19) inhibitor (IC50 = 0.4 and 0.12 nM at rat ovary and human placenta cells, respectively) that weakly inhibits the synthesis o...
LY 43578 is an aromatase inhibitor.
FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast c...
ORG 30958 is a potent aromatase inhibitor in vivo. ORG 30958 proved to be devoid of antiestrogenic activity which indicates that the absence of cornification of...