LY 344864 - CAS 186544-26-3
Catalog number: 186544-26-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H22FN3O
Molecular Weight:
351.42
COA:
Inquire
Targets:
5-HT Receptor
Description:
LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 µM for SR-1F, SR-1A, SR-1B
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Purity:
>99 %
Appearance:
White to off-white solid
Synonyms:
N-[(6R)-6-(dimethylamino)-6,7,8,9-tetrahydro-5H-carbazol-3-yl]-4-fluorobenzamide;hydrochloride LY 344864 LY344864
Solubility:
Soluble to > 10 mM in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -74℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Boiling Point:
471.9±45.0 °C | Condition: Press: 760 Torr
Density:
1.28±0.1 g/cm3
InChIKey:
OKUHLSYESBLBCP-PKLMIRHRSA-N
InChI:
1S/C21H22FN3O.ClH/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13;/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26);1H/t16-;/m1./s1
Canonical SMILES:
CN(C)C1CCC2=C(C1)C3=C(N2)C=CC(=C3)NC(=O)C4=CC=C(C=C4)F.Cl
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CAS 186544-26-3 LY 344864

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