LY-3177833 - CAS 1627696-51-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H12FN5O
Molecular Weight:
309.3
COA:
Inquire
Targets:
Cdc7
Description:
LY-3177833 is a selective CDC7 (IC50 = 3.3 nM) and pMCM2 (IC50 = 290nM) inhibitor. It exhibits an antitumor activity in a wide range of cancers.
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Brife Description:
CDC7 and pMCM2 inhibitor, cancers
Appearance:
Solid powder
Synonyms:
(3R)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one; LY-3177833; LY 3177833; LY3177833
MSDS:
Inquire
Application:
antitumor drug
InChIKey:
KNLVLWZENYQYRT-MRXNPFEDSA-N
InChI:
1S/C16H12FN5O/c1-16(14-13(17)7-18-8-19-14)12-3-2-9(10-5-20-21-6-10)4-11(12)15(23)22-16/h2-8H,1H3,(H,20,21)(H,22,23)/t16-/m1/s1
Canonical SMILES:
O=C1N[C@@](C)(C2=NC=NC=C2F)C3=C1C=C(C4=CNN=C4)C=C3
Current Developer:
Lilly
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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LY-3177833
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LY-3177833 is a selective CDC7 (IC50 = 3.3 nM) and pMCM2 (IC50 = 290nM) inhibitor. It exhibits an antitumor activity in a wide range of cancers.

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