LY 302148 - CAS 182564-47-2
Catalog number:
182564-47-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H23FN4
Molecular Weight:
326.42
COA:
Inquire
Targets:
5-HT Receptor
Description:
LY 302148 is a 5-HT1F receptor agonist with potential for migraine therapeutics.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Appearance:
Solid powder
Synonyms:
5-fluoro-3-[1-[2-(1-methylpyrazol-4-yl)ethyl]piperidin-4-yl]-1H-indole; 5-fluoro-3-(1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-4-piperidinyl)-1H-indole; LY 302148; LY 302148, monohydrochloride; LY-302148
MSDS:
Inquire
InChIKey:
RFIDURCIAHBFRJ-UHFFFAOYSA-N
InChI:
InChI=1S/C19H23FN4/c1-23-13-14(11-22-23)4-7-24-8-5-15(6-9-24)18-12-21-19-3-2-16(20)10-17(18)19/h2-3,10-13,15,21H,4-9H2,1H3
Canonical SMILES:
CN1C=C(C=N1)CCN2CCC(CC2)C3=CNC4=C3C=C(C=C4)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products


CAS 106266-06-2 Risperidone

Risperidone
(CAS: 106266-06-2)

Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.

Naronapride
(CAS: 860174-12-5)

Naronapride is a selective 5-HT(4) receptor agonist for gastrointestinal motility disorders. It can accelerate overall colonic transit and tend to accelerate GE...

CAS 59729-32-7 Citalopram hydrobromide

Citalopram hydrobromide
(CAS: 59729-32-7)

Citalopram Hydrobromide is an inhibitor of serotonin (5-HT) uptake used as an antidepressant.

Agomelatine hydrochloride
(CAS: 1176316-99-6)

The hydrochloride salt form of Agomelatine that is an antidepressant agent for acting as an antagonism of the 5-HT2C receptor. It is also an antagonist of 5-HT2...

CAS 261901-57-9 SB-269970 hydrochloride

SB-269970 hydrochloride
(CAS: 261901-57-9)

SB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other recept...

GYKI-46903 HCl
(CAS: 142999-59-5)

GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...

CAS 359625-79-9 CYR-101

CYR-101
(CAS: 359625-79-9)

MIN-101, a novel cyclic amide derivative, is a 5-HT2A and sigma 2 receptor antagonist (Ki= 7.53 nM for 5-HT2A and 8.19 nM for sigma-2, respectively).

CAS 3200-06-4 Nafronyl oxalate

Nafronyl oxalate
(CAS: 3200-06-4)

Naftidrofuryl, being useful in enhancing cellular oxidative, could be used as a vasodilator in the treatment of peripheral and cerebral vascular disorders.

CAS 181183-52-8 Almotriptan Malate

Almotriptan Malate
(CAS: 181183-52-8)

Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.

CAS 111974-72-2 Quetiapine Fumarate

Quetiapine Fumarate
(CAS: 111974-72-2)

Quetiapine Fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

CAS 57477-39-1 BRL-54443

BRL-54443
(CAS: 57477-39-1)

BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.

CAS 37115-32-5 Adinazolam

Adinazolam
(CAS: 37115-32-5)

Adinazolam, a triazolobenzodiazepine, a high affinity for β-adrenoceptors (Kd = 0.061 nM) and alters the expression of serotonin 5-HT2 receptors in rat fronto-p...

CAS 72797-41-2 Tianeptine

Tianeptine
(CAS: 72797-41-2)

Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo with psychostimulant, anti-ulcer and anti-emetic properties.

CAS 442-51-3 Harmine

Harmine
(CAS: 442-51-3)

Harmine induces apoptosis and inhibits proliferation, migration and invasion of human gastric cancer cells, which may be mediated by down-regulation of COX-2 ex...

CAS 222551-17-9 Adoprazine

Adoprazine
(CAS: 222551-17-9)

Adoprazine, also known as SLV 313, with potential antipsychotic property, is a agonist of cloned h5-HT(1A) receptors (pEC(50)=9.0) and a full antagonist of hD(2...

CAS 121679-13-8 Naratriptan

Naratriptan
(CAS: 121679-13-8)

Naratriptan, a 5-HT1B/1D receptor agonist, could be used in the treatment of migraine.

CAS 103639-04-9 Ondansetron Hydrochloride Dihydrate

Ondansetron Hydrochloride Dihydrate
(CAS: 103639-04-9)

Ondansetron hydrochloride dihydrate is a specific and competitive antagonist of serotonin 5-HT3 receptor (Ki = 0.77 nM) with anxiolytic and neuroleptic activiti...

CAS 1331782-27-4 PF-04995274

PF-04995274
(CAS: 1331782-27-4)

PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (A...

CAS 189188-57-6 Tegaserod maleate

Tegaserod maleate
(CAS: 189188-57-6)

Tegaserod maleate is a partial agonist of the 5-HT4 receptor (Ki = 12 nM) that can treat irritable bowel syndrome (IBS).

CAS 193611-72-2 BRL-15572

BRL-15572
(CAS: 193611-72-2)

BRL-15572 displays high affinity and selectivity for h5-HT1D receptors. BRL-15572 has 60-fold higher affinity for h5-HT1D than 5-HT1B receptors.

Quick Inquiry

Verification code

Featured Items