LY-293559 - CAS 150010-68-7
Catalog number: 150010-68-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C13H21N5O2
Molecular Weight:
279.34
COA:
Inquire
Targets:
AMPAR
Description:
LY 215490, a decahydroisoquinoline derivative, has been found to be an AMPA receptor antagonist that could be a neuroprotective agent in the study of focal ischaemia.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
LY-293559; LY 215490; LY-215490; CHEMBL70937; SCHEMBL3678843; ZINC5760; (3R,4aS,6S,8aS)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
ZXFRFPSZAKNPQQ-ZRUFSTJUSA-N
InChI:
InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m0/s1
Canonical SMILES:
C1CC2CNC(CC2CC1CCC3=NNN=N3)C(=O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related AMPAR Products


CAS 118876-58-7 NBQX

NBQX
(CAS: 118876-58-7)

This active molecular is an AMPA receptor antagonist which blocks AMPA receptors in 10-20µM concentrations. It is also a Glutamate receptor antagonist. NBQX was...

LY-293559
(CAS: 150010-68-7)

LY 215490, a decahydroisoquinoline derivative, has been found to be an AMPA receptor antagonist that could be a neuroprotective agent in the study of focal isch...

CAS 215923-54-9 CX546

CX546
(CAS: 215923-54-9)

It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine dru...

CAS 77472-70-9 4-Phenyl-2-pyrrolidone-1-acetamide

4-Phenyl-2-pyrrolidone-1-acetamide
(CAS: 77472-70-9)

4-Phenyl-2-pyrrolidone-1-acetamide is a GABA derivative that exhibited apparent immunocorrection properties during immunosuppression induced by cyclophosphamide...

CAS 220445-20-5 GYKI-47261

GYKI-47261
(CAS: 220445-20-5)

GYKI-47261 is a non-competitive AMPA receptor antagonist (IC50 = 2.5 μM) and a CYP2E1 inducer. GYKI-47261 shows broad spectrum anticonvulsive activity and neuro...

CAS 22503-72-6 IDRA-21

IDRA-21
(CAS: 22503-72-6)

IDRA-21, an analog of cyclothiazide, inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 inhibits synaptic and extrasy...

NS-1209
(CAS: 245063-59-6)

NS-1209, an AMPA/GluR5 receptor antagonist, is a antiepileptic drug candidate currently under clinical trials.

GYKI 53784
(CAS: 161832-71-9)

GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at ...

CAS 380607-77-2 CMPDA

CMPDA
(CAS: 380607-77-2)

CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges.

LY-326325
(CAS: 177314-99-7)

LY-326325, a decahydroisoquinaline derivative, has been found to be an AMPA receptor antagonist and was once studied for neuroprotection.

CAS 122306-11-0 Naspm

Naspm
(CAS: 122306-11-0)

A poliamine amide as potent Spermidine uptake inhibitor.

CAS 1026791-61-6 Org-26576

Org-26576
(CAS: 1026791-61-6)

Org-26576 is a positive allosteric modulator of AMPA receptor. Org-26576 increases the anteroventral and laterodorsal thalamus, cingulate cortex, dentate gyrus ...

EGIS-8332
(CAS: 220725-87-1)

EGIS-8332 potently decreased AMPA and quisqualate induced LDH release (IC50 = 5.2 ± 0.4 and 7.4 ± 1.3 μM, respectively) from the cells. The inhibition of the AM...

CAS 199655-36-2 CP 465022

CP 465022
(CAS: 199655-36-2)

CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat ...

CAS 1255517-78-2 ZK200775 hydrate

ZK200775 hydrate
(CAS: 1255517-78-2)

ZK200775 hydrate(Fanapanel; MPQX) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 &mu...

CAS 143691-37-6 LY 293606

LY 293606
(CAS: 143691-37-6)

GYKI-53405 is a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor) antagonist. It can bind to Xenopus brain membranes ...

CAS 161832-65-1 Talampanel

Talampanel
(CAS: 161832-65-1)

Talampanel, also known as LY300164 and GYKI-53773, is a glutamate receptor inhibitor with anti-seizure activity. Talampanel is also an orally active, potent an...

CAS 143692-18-6 GYKI 53655

GYKI 53655
(CAS: 143692-18-6)

GYKI 53655 is a selective AMPA receptor antagonist with anticonvulsant activity.

CAS 157115-85-0 Noopept

Noopept
(CAS: 157115-85-0)

Noopept is a nootropic and neuroprotective drug that normalizes the balance of the pro- and antioxidant systems. Noopept modulates a variety of physiological fu...

GYKI-52466
(CAS: 102771-26-6)

GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anti...

Quick Inquiry

Verification code

Featured Items