LY 293284 - CAS 141318-62-9
Catalog number: 141318-62-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
5-HT Receptor
LY-293284 is a Serotonin 1A receptor agonist developed by Eli Lilly. It is a selective 5-HT1A receptor full agonist. LY-293284 is far more selective for 5-HT1A with over 1000x selectivity over other serotonin receptor subtypes and other targets. No development was reported for the treatment of Anxiety disorders and Major depressive disorder.
Publictions citing BOC Sciences Products
  • >> More
Soluble in DMSO
-20°C Freezer
Anxiety disorders; Major depressive disorder
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Canonical SMILES:
Current Developer:
Eli Lilly; Nonindustrial source
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products

CAS 158876-82-5 Rupatadine

(CAS: 158876-82-5)

Rupatadine, with the potential to treat allergic rhinitis and urticaria, is a potent and long-lasting dual antagonist of PAF/H1. in vitro: Without affecting con...

R 1485 dihydrochloride

R 1485 dihydrochloride is a selective and high affinity 5-HT6 antagonist (pKi = 8.9), with >100 fold selectivity against a panel of 50 targets including other 5...

CAS 185259-85-2 GR 46611

GR 46611
(CAS: 185259-85-2)

GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system.

CAS 155584-74-0 VUF 10166

VUF 10166
(CAS: 155584-74-0)

VUF 10166 is a potent and competitive 5-HT3 receptor antagonist (IC50 = 0.04 and 22 nM for human 5HT3A and 5-HT3AB receptors, respectively). VUF 10166 exhibits ...

CAS 263744-72-5 EMDT oxalate

EMDT oxalate
(CAS: 263744-72-5)

EMDT oxalate is a selective 5-HT6 agonist (Ki = 16 nM at human 5-HT6 receptors) with antidepressant-like activity. It shows potency comparable to serotonin for ...

CAS 350992-13-1 Bifeprunox mesylate

Bifeprunox mesylate
(CAS: 350992-13-1)

Bifeprunox mesylate is a dopamine D2 and 5-HT1A partial agonist developed as an atypical antipsychotic for the treatment of schizophrenia and other psychotic in...

CAS 866933-46-2 Velusetrag

(CAS: 866933-46-2)

Velusetrag is a selective, 5-HT4receptor agonist. Phase II clinical trials for the treatment of gastroparesis are on-going. Clnical trials for Alzheimer's disea...

CAS 158930-09-7 Frovatriptan Succinate

Frovatriptan Succinate
(CAS: 158930-09-7)

Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.

CAS 1217756-94-9 LY 344864 hydrochloride

LY 344864 hydrochloride
(CAS: 1217756-94-9)

LY 344864 hydrochloride is a 5-HT1F receptor agonist with EC50 value of 3 nM.

CAS 76135-31-4 8-Hydroxy-DPAT hydrobromide

8-Hydroxy-DPAT hydrobromide
(CAS: 76135-31-4)

8-Hydroxy-DPAT hydrobromide is a selective 5-HT1A agonist with moderate affinity for 5-HT7 receptors (pKi = 6.6 at the human 5-HT7 receptor expressed in HEK 293...

CAS 154323-57-6 Almotriptan

(CAS: 154323-57-6)

Almotriptan, also called as Almogran, is a agonist with high and specific affinity for 5-HT1B/1D receptors. developed by Almirall Prodesfarma for the acute trea...

CAS 144734-36-1 4F 4PP oxalate

4F 4PP oxalate
(CAS: 144734-36-1)

4F 4PP oxalate is a selective 5-HT2A antagonist with almost as high affinity (Ki = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki = 6...

CAS 13707-88-5 Alprenolol hydrochloride

Alprenolol hydrochloride
(CAS: 13707-88-5)

Alprenolol hydrochloride is the hydrochloride salt of alprenolol, which is a non-selective 5-HT1A receptor antagonist and beta blocker. It is used in the treatm...

CAS 155204-23-2 p-MPPI

(CAS: 155204-23-2)

p-MPPI is a selective 5-HT1A antagonist.

CAS 10457-90-6 Bromperidol

(CAS: 10457-90-6)

Bromperidol, a derivative of butyrophenone, is an antipsychotic commonly used in the treatment of schizophrenia as it could bind to the D2 dopamine and 5-HT2A s...

CAS 134296-40-5 BIMU 8

(CAS: 134296-40-5)

BIMU 8 is a potent and selective 5-HT4 receptor full agonist (KD = 77 nM and EC50 = 18 nM for wild type 5-HT4 receptors).

CAS 197446-42-7 (S)-(-)-8-Methoxy-2-aminotetraline hydrochloride

(S)-(-)-8-Methoxy-2-aminotetraline hydro
(CAS: 197446-42-7)

(S)-(-)-8-Methoxy-2-Aminotetraline hydrochloride is a 5-HT1A agonist.

CAS 149055-79-8 WAY 100135 dihydrochloride

WAY 100135 dihydrochloride
(CAS: 149055-79-8)

WAY 100135 dihydrochloride is a selective 5-HT1A antagonist (IC50 = 15 nM).

CAS 137328-52-0 LY 215840

LY 215840
(CAS: 137328-52-0)

LY 215840 is a potent antagonist of both Serotonin 2A receptor and Serotonin 7 receptor. It can reduce stimulatory effect of serotonin on aldosterone secretion ...

CAS 271780-64-4 LY 393558

LY 393558
(CAS: 271780-64-4)

LY 393558 is a 5-HT reuptake inhibitor with pIC50 value of 8.48. It is also a dual 5-HT1B/1D receptor antagonist with pKB values of 9.05 and 8.98 respectively.

Quick Inquiry

Verification code

Featured Items