LY 293284 - CAS 141318-62-9
Catalog number: 141318-62-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H26N2O
Molecular Weight:
298.43
COA:
Inquire
Targets:
5-HT Receptor
Description:
LY-293284 is a Serotonin 1A receptor agonist developed by Eli Lilly. It is a selective 5-HT1A receptor full agonist. LY-293284 is far more selective for 5-HT1A with over 1000x selectivity over other serotonin receptor subtypes and other targets. No development was reported for the treatment of Anxiety disorders and Major depressive disorder.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
(R)-1-(4-(dipropylamino)-1,3,4,5-tetrahydrobenz(cd)indol-6-yl)-Ethanone
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Anxiety disorders; Major depressive disorder
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
CKYZLYQSDNLGPT-HNNXBMFYSA-N
InChI:
1S/C19H26N2O/c1-4-8-21(9-5-2)15-10-14-12-20-18-7-6-16(13(3)22)17(11-15)19(14)18/h6-7,12,15,20H,4-5,8-11H2,1-3H3/t15-/m0/s1
Canonical SMILES:
C(C)(c1c2c3c(c[nH]c3cc1)C[C@@H](C2)N(CCC)CCC)=O
Current Developer:
Eli Lilly; Nonindustrial source
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products


LY 426965 dihydrochloride

LY 426965 dihydrochloride is a potent and selective 5-HT1A antagonist that is more active than its opposite enantiomer (R)-(-)-LY 426965.

CAS 13523-86-9 Pindolol

Pindolol
(CAS: 13523-86-9)

Pindolol, an Indole derivative, could be used in the treatment of hypertension and arrhythmia for acting as a 5-HT1A/1B receptor antagonist. IC50: 33nM(Ki).

CAS 30123-17-2 Tianeptine sodium

Tianeptine sodium
(CAS: 30123-17-2)

Tianeptine sodium is a selective serotonin reuptake enhancer (SSRE), used for treating major depressive episodes.

CAS 135722-25-7 S 14506

S 14506
(CAS: 135722-25-7)

S 14506 is a potent and selective 5-HT1A agonist.

CAS 25332-39-2 Trazodone hydrochloride

Trazodone hydrochloride
(CAS: 25332-39-2)

Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. It is a ...

CAS 64022-27-1 MK212

MK212
(CAS: 64022-27-1)

MK212 is a 5HT2C-receptor agonist. It exhibited anxiolytic activity in mice at low doses. It is a serotonin agonist. It could promote the secretion of serum pro...

CAS 228418-85-7 (R)-(-)-LY 426965 dihydrochloride

(R)-(-)-LY 426965 dihydrochloride
(CAS: 228418-85-7)

(R)-(-)-LY 426965 dihydrochloride is a selective 5-HT1A antagonist that is less active than its opposite (S)-(+)-enantiomer LY 426965.

CAS 607742-55-2 SB 742457 hydrochloride

SB 742457 hydrochloride
(CAS: 607742-55-2)

SB 742457 hydrochloride is a selective 5-HT6 antagonist with >100-fold selectivity over other receptors. It is a potential agent added to stabilize donepezil tr...

CAS 115956-13-3 Dolasetron mesylate

Dolasetron mesylate
(CAS: 115956-13-3)

The mesylate salt form of Dolasetron which is a pseudopelletierine derivative and could be used to relieve the nausea and vomiting caused by chemotherapy for be...

CAS 59729-32-7 Citalopram hydrobromide

Citalopram hydrobromide
(CAS: 59729-32-7)

Citalopram Hydrobromide is an inhibitor of serotonin (5-HT) uptake used as an antidepressant.

Lu AE58054
(CAS: 467459-31-0)

Lu AE58054 is a selective and high affinity 5-HT6 receptor antagonist as promising treatment for cognitive disorders.

CAS 121679-13-8 Naratriptan

Naratriptan
(CAS: 121679-13-8)

Naratriptan, a 5-HT1B/1D receptor agonist, could be used in the treatment of migraine.

CAS 135159-51-2 Sarpogrelate hydrochloride

Sarpogrelate hydrochloride
(CAS: 135159-51-2)

The hydrochloride salt form of Sarpogrelate, a 5-HT2 antagonist, could be used as an antiplatelet agent and other sorts of disease like angina pectoris, diabete...

CAS 6202-23-9 Cyclobenzaprine HCl

Cyclobenzaprine HCl
(CAS: 6202-23-9)

Cyclobenzaprine HCl is a muscle relaxant, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the sp...

CAS 145202-66-0 Rizatriptan Benzoate

Rizatriptan Benzoate
(CAS: 145202-66-0)

Rizatriptan Benzoate is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.

CAS 107429-63-0 Lintopride

Lintopride
(CAS: 107429-63-0)

Lintopride, also called as ACEMM, a new benzamid, is a 5HT4 antagonist with moderate 5HT3 antagonist properties that increases gastric emptying, stimulates antr...

CAS 866933-46-2 Velusetrag

Velusetrag
(CAS: 866933-46-2)

Velusetrag is a selective, 5-HT4receptor agonist. Phase II clinical trials for the treatment of gastroparesis are on-going. Clnical trials for Alzheimer's disea...

BMS-180048
(CAS: 171171-42-9)

BMS-180048, also know as Avitriptan Fumarate, has been found to be a5HT-1B/1D-receptor agonist that was once studied as an anti-migraine agent.

CAS 146939-27-7 Ziprasidone

Ziprasidone
(CAS: 146939-27-7)

Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist like other atypical antipsychotic agents. Ziprasidone targets dopamine neurotransmis...

CAS 361-37-5 Methysergide

Methysergide
(CAS: 361-37-5)

Methysergide is an ergot derivative that is a congener of lysergic acid diethylamide for the treatment of vascular headache

Quick Inquiry

Verification code

Featured Items