LY 269415 - CAS 132392-65-5
Catalog number:
132392-65-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H28N2O2S
Molecular Weight:
348.51
COA:
Inquire
Targets:
5-Lipoxygenase
Description:
LY 269415 is a 5-Lipoxygenase inhibitor originated by Eli Lilly. It is a potent antioxidant with antiinflammatory properties in vitro. But no development was reported for Rheumatic disorders in USA.
Publictions citing BOC Sciences Products
  • >> More
Purity:
98%
Appearance:
Powder
Synonyms:
5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-3-(methylamino)-4-Thiazolidinone
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Rheumatic disorders
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
NKDHVZVNBMVYKJ-GDNBJRDFSA-N
InChI:
1S/C19H28N2O2S/c1-18(2,3)13-8-12(9-14(16(13)22)19(4,5)6)10-15-17(23)21(20-7)11-24-15/h8-10,20,22H,11H2,1-7H3/b15-10-
Canonical SMILES:
S1CN(C(\C1=C\c1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)=O)NC
Current Developer:
Originator Eli Lilly
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-Lipoxygenase Products


CAS 91431-42-4 RS4317

RS4317
(CAS: 91431-42-4)

A topically effective inhibitor of 5-lipoxygenase (5-LO)

CAS 1532593-30-8 ML355

ML355
(CAS: 1532593-30-8)

ML355 inhibits PAR-4 induced aggregation and calcium mobilization in human platelets and reduce 12-HETE in β-cells.

CAS 102271-49-8 PGS-IN-1

PGS-IN-1
(CAS: 102271-49-8)

PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) (IC50= 0.28 μM) and also an inhibitor of 5-lipoxygenase (IC50= 1.05 μM).

ICI 211965
(CAS: 129424-08-4)

ICI 211965 is a selective 5-lipoxygenase inhibitor and it may be useful in regulating production of those interleukins involved in joint cartilage destruction.

PF04191834
(CAS: 1029317-21-2)

PF04191834 is a novel, potent and selective non-redox 5-lipoxygenase(5-LOX) inhibitor with an IC50 value of 229 +/- 20 nM. It inhibits 5-LOX in human blood cell...

FR 110302
(CAS: 119256-94-9)

This active molecular is a potent 5-lipoxygenase inhibitor which was originated by Fujisawa company for treating asthma. No-Development was reported for asthma ...

CAS 154355-75-6 COX/5-LO-IN-1

COX/5-LO-IN-1
(CAS: 154355-75-6)

A dual inhibitor of cylooxygenase and 5-lipoxygenase

PD 127443
(CAS: 121502-05-4)

This active molecular is a Leukotriene B4 antagonist. PD- 127443 is also a 5-lipoxygenase and cyclooxygenase inhibitor and it has been reported to have antiinfl...

CAS 59937-28-9 Malotilate

Malotilate
(CAS: 59937-28-9)

Malotilate, diisopropyl 1,3-dithiol-2-ylidenemalonate, is a drug used for the treatment of liver cirrhosis.

LY 269415
(CAS: 132392-65-5)

LY 269415 is a 5-Lipoxygenase inhibitor originated by Eli Lilly. It is a potent antioxidant with antiinflammatory properties in vitro. But no development was re...

CAS 132956-22-0 Enazadrem phosphate

Enazadrem phosphate
(CAS: 132956-22-0)

Enazadrem phosphate is a 5-lipoxygenase inhibitor as an Antipsoriatic agent.

CAS 118569-21-4 Zileuton sodium

Zileuton sodium
(CAS: 118569-21-4)

Zileuton sodium is an inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes(LTB4, LTC4, LTD4 and LTE4) formation with an IC50 value of 0.5μM. Zileuton sod...

CAS 120210-48-2 Tenidap

Tenidap
(CAS: 120210-48-2)

Tenidap is one of the nonsteroidal antiinflammatory drugs. It is a COX1/2 and 5-lipoxygenase inhibitor. Tenidap preferentially inhibits COX-1 and IC50 value is...

CAS 111406-87-2 Zileuton

Zileuton
(CAS: 111406-87-2)

Zileuton is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms o...

CAS 205654-37-1 CMI-392

CMI-392
(CAS: 205654-37-1)

CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM).

Quick Inquiry

Verification code

Featured Items