LXS196 - CAS 1874276-76-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H23F3N8O
Molecular Weight:
472.47
COA:
Inquire
Targets:
PKC
Description:
LXS196 is a potent and orally active protein kinase C (PKC) inhibitor under clinical trials for the treatment of uveal melanoma, the most common cancer of the eye in adults.
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Synonyms:
3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamide; LXS 196; LXS-196
Solubility:
DMSO: ≥100 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
592.7±50.0 ℃ at 760 Torr
Density:
1.387±0.06 g/cm3
InChIKey:
XXJXHXJWQSCNPX-UHFFFAOYSA-N
InChI:
1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)
Canonical SMILES:
CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N
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Chemical Structure

CAS 1874276-76-2 LXS196

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