Lusutrombopag - CAS 1110766-97-6
Catalog number:
1110766-97-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C29H32Cl2N2O5S
Molecular Weight:
591.54
COA:
Inquire
Targets:
Thrombopoietin Receptor
Description:
Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist. It acts selectively on the human TPO receptor and activates signal transduction pathways and thereby increases platelet levels. It was developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. It has been listed.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
S888711;S-888711;(E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Lusutrombopag was used for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Density:
1.299±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
NOZIJMHMKORZBA-KJCUYJGMSA-N
InChI:
InChI=1S/C29H32Cl2N2O5S/c1-5-6-7-8-12-38-18(3)20-10-9-11-21(26(20)37-4)25-16-39-29(32-25)33-27(34)19-14-23(30)22(24(31)15-19)13-17(2)28(35)36/h9-11,13-16,18H,5-8,12H2,1-4H3,(H,35,36)(H,32,33,34)/b17-13+/t18-/m0/s1
Canonical SMILES:
CCCCCCOC(C)C1=CC=CC(=C1OC)C2=CSC(=N2)NC(=O)C3=CC(=C(C(=C3)Cl)C=C(C)C(=O)O)Cl
Current Developer:
Lusutrombopag was developed by Shionogi and has been listed.
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