Lusaperidone - CAS 214548-46-6
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H21N3O2
Molecular Weight:
359.42
COA:
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Targets:
Adrenergic Receptor
Description:
Lusaperidone, also known as R107474, is an α2 adrenergic receptor antagonist. R107474 showed high affinity for ha2A-, ha2B-, and ha2C-adrenoceptors, stably expressed in CHO cells. The compound bound preferentially to the ha2A- and ha2C-adrenoceptor subtypes (Ki = 0.13 and 0.15 nM, respectively) and was seven times less potent in binding to the ha2B-adrenoceptors (Ki = 1.03 nM).
Synonyms:
3-[2-(3,4-dihydro-1H-[1]benzofuro[3,2-c]pyridin-2-yl)ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one; R107474
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
538.3±60.0 ℃ at 760 Torr
Density:
1.31±0.1 g/cm3
InChIKey:
ZYXHQIPQIKTEDI-UHFFFAOYSA-N
InChI:
1S/C22H21N3O2/c1-15-16(22(26)25-11-5-4-8-21(25)23-15)9-12-24-13-10-20-18(14-24)17-6-2-3-7-19(17)27-20/h2-8,11H,9-10,12-14H2,1H3
Canonical SMILES:
CC1=C(C(=O)N2C=CC=CC2=N1)CCN3CCC4=C(C3)C5=CC=CC=C5O4
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CAS 214548-46-6 Lusaperidone

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