|Description||LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR). It was found to be an allosteric enhancer of Emax. It exerted an Emax-enhancing effect at a concentration of 0.1 microM or higher. It was shown to increase the Emax of Cl-IB-MECA and other low-efficacy agonists to a larger extent than that of the high-efficacy agonist NECA. It converted a nucleoside A3 AR antagonist MRS542. It has anti-inflammatory effect.|
|Solubility||10 mM in DMSO|
|Application||LUF6000 has anti-inflammatory effect.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||650.5±55.0 °C | Condition: Press: 760 Torr|
|Melting Point||237-240 °C | Condition: Solv: methanol (67-56-1); water (7732-18-5)|
|Density||1.401±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
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