Lu AF21934 - CAS 1445605-23-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C14H16Cl2N2O2
Molecular Weight:
315.2
COA:
Inquire
Targets:
mGluR
Description:
Lu AF21934 is a selective and brain-penetrating positive allosteric modulator (PAM) of mGlu4 receptors (IC50= 500 nM) on the harmaline-induced tremor and other forms of motor activity in rats using fully automated Force Plate Actimeters.
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Brife Description:
A positive allosteric modulator of mGlu4 receptors
Synonyms:
(1R,2S)-2-N-(3,4-dichlorophenyl)cyclohexane-1,2-dicarboxamide; Lu AF21934; N1-(3,4-dichlorophenyl)-cyclohexane-1,2-dicarboxamide
Solubility:
DMSO: ≥ 80 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
577.6±50.0 ℃ at 760 Torr
Density:
1.386±0.06 g/cm3
InChIKey:
AVKZWCJNDWOBAM-ZJUUUORDSA-N
InChI:
1S/C14H16Cl2N2O2/c15-11-6-5-8(7-12(11)16)18-14(20)10-4-2-1-3-9(10)13(17)19/h5-7,9-10H,1-4H2,(H2,17,19)(H,18,20)/t9-,10+/m1/s1
Canonical SMILES:
C1CCC(C(C1)C(=O)N)C(=O)NC2=CC(=C(C=C2)Cl)Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1445605-23-1 Lu AF21934

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