|Description||LTX-315, an oncolytic peptide with potent anticancer activity, kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization. LTX-315 inhibits MRC-5, A20 and AT84 with IC50s of 34.3, 8.3 and 11 µM, respectively.|
|Synonyms||H-Lys-Lys-Trp-Trp-Lys-Lys-Trp-Dip-Lys-NH2; L-lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-3,3-diphenyl-L-alanyl-L-lysinamide; (2S)-2,6-diamino-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]hexanamide|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||1700.2±65.0 ℃ at 760 Torr|
AG-1801is a bio-active chemical for treatment of cell proliferative diseases.
The deuterium labeled β-Apo-13-carotenone which is an antagonist of RXRα.
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