|Description||The sulfate salt form of LOXO-101, also called Larotrectinib, is a ATP-competitive inhibitor of tropomyosin receptor kinases and is still under Phase II clinical triall for Solid tumours. IC50: 2 - 20 nM.|
|Synonyms||LOXO-101 (sulfate); Larotrectinib sulfate; ARRY-470 sulfate; LOXO-101 sulfate; UNII-RDF76R62ID; RDF76R62ID|
|Solubility||DMSO: ≥ 31 mg/mL|
|Application||The sulfate salt form of LOXO-101 which is a ATP-competitive inhibitor of tropomyosin receptor kinases.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
|Current Developer||Loxo Oncology|
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