Losartan Potassium Salt - CAS 124750-99-8
Catalog number: 124750-99-8
Molecular Formula:
C22H22ClN6OK
Molecular Weight:
461
COA:
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Description:
Losartan is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. It promotes vasodilatation and counteracts the effects of aldosterone thus can be used as an antihypertensive.
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Brife Description:
angiotensin II receptor antagonist, antihypertensive
Purity:
>98%
Appearance:
White to Off-White Solid
Synonyms:
MK 954; Cozaar; Lorzaar; Losaprex; Hyzaar; [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
MSDS:
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Application:
antihypertensive
Shelf Life:
2 years
Quantity:
Milligrams-Grams
Boiling Point:
682 °C
Melting Point:
>259°C (subl.)
InChIKey:
OXCMYAYHXIHQOA-UHFFFAOYSA-N
InChI:
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Canonical SMILES:
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
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Chemical Structure

CAS 124750-99-8 Losartan Potassium Salt

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