Losartan potassium - CAS 124750-99-8
Catalog number: B0046-464141
Category: APIs
Molecular Formula:
C22H23ClKN6O
Molecular Weight:
462.01
COA:
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Description:
Losartan is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. It promotes vasodilatation and counteracts the effects of aldosterone thus can be used as an antihypertensive.
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Catalog Number Size Price Stock Quantity
B0046-464141 25 g $298 In stock
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Brife Description:
angiotensin II receptor antagonist, antihypertensive
Purity:
>98%
Appearance:
White to Off-White Solid
Synonyms:
MK 954; Cozaar; Lorzaar; Losaprex; Hyzaar; [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
MSDS:
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Application:
antihypertensive
Shelf Life:
2 years
Boiling Point:
682 °C
Melting Point:
>259°C (subl.)
InChIKey:
OXCMYAYHXIHQOA-UHFFFAOYSA-N
InChI:
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
Canonical SMILES:
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
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Chemical Structure

CAS 124750-99-8 Losartan potassium

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