|Description||Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.|
A potent and selective inhibitor of E-selectin (IC50= 7 nM) and ICAM-1 (IC50= 5 nM)
4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine, a nonpolar, essential amino acid that naturally occurs in the human body and is also used...
Botanical Source from Bufo bufo gargarizans and Bufo formosus, used for microbial transformation.
Lubiprostone induces a robust secretory response in T84 monolayers. Lubiprostone induces a rise in cAMP levels that was sensitive to EP(4)-receptor blockage in ...
Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD).
Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo.
YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).YK-4-279 eliminates cyclin D levels by blocking the interaction of EWS-FLI1 with RHA ...
R-(-)-Arundic Acid, also called as ONO 2506, is an astrocyte modulating agent which can treat neurodegenerative diseases including Alzheimer's disease and Parki...
TAT peptide, derived from the transactivator of transcription (TAT) of human immunodeficiency virus, is a cell penetrating peptide (GRKKRRQRRRPQ).
Omeprazole sulphone is the major metabolite of omeprazole, which is the gastric proton pump inhibitor. It is produced by cytochrome P450 (CYP)3A4 sulfoxidation ...
KT 5926, an organic heterooctacyclic compound, selectively inhibits nerve growth factor-dependent neurite elongation.
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity o...
Rosmarinic acid is a naturally occurring hydroxylated compound occured in many plants. Rosmarinic acid exhibits agonist activity at GPR35 and shows antiviral, a...
WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM). ABHD6 is a serine hydrolase that is highly expressed in mammalian brain.
GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-29...
L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. It is an α-amino acid...
CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in a...
Emiglitate is an α-glucosidase inhibitor that is a powerful inhibitor of glucose-induced insulin release.But no development was reported for the treatment of Di...
AG-5507 is a bio-active chemical howerver, its detailed information has not been published.
Cysteamine has been shown to increase intracellular glutathione levels in cystinotic cells, thus restoring the altered redox state of the cells.