|Description||Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment.|
|Appearance||white solid powder|
|Synonyms||Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine.|
|Current Developer||KuDOS Pharmaceuticals Ltd. and AstraZeneca|
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