LMI070 - CAS 1562338-42-4
Catalog number: 1562338-42-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H27N5O2
Molecular Weight:
393.48
COA:
Inquire
Targets:
DNA/RNA Synthesis
Description:
LMI070, also called as NVS-SM1, is a selective, high plasma exposure and orally active modulator of SMN2 splicing which demonstrates robust activity across disease-relevant induced pluripotent stem cell (iPSc)-derived neurons. in vivo: oral administration
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Appearance:
Solid powder
Synonyms:
(6E)-3-(1H-pyrazol-4-yl)-6-[3-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-1H-pyridazin-6-ylidene]cyclohexa-2,4-dien-1-one UNII-P12R69543A P12R69543A Branaplam Branaplam [INN] SCHEMBL15475826 LMI-070 1562338-42-4 Phenol, 5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetra
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -87℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
660.0±55.0 °C | Condition: Press: 760 Torr
Density:
1.171±0.06 g/cm3
InChIKey:
YIFFDXMJVNKGBL-ISLYRVAYSA-N
InChI:
1S/C22H27N5O2/c1-21(2)10-16(11-22(3,4)27-21)29-20-8-7-18(25-26-20)17-6-5-14(9-19(17)28)15-12-23-24-13-15/h5-9,12-13,16,25,27H,10-11H2,1-4H3,(H,23,24)/b18-17+
Canonical SMILES:
CC1(CC(CC(N1)(C)C)OC2=NNC(=C3C=CC(=CC3=O)C4=CNN=C4)C=C2)C
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