LKB1/AAK1 dual inhibitor - CAS 1093222-27-5
Catalog number:
1093222-27-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H13N5O
Molecular Weight:
339.35
COA:
Inquire
Targets:
Pim
Description:
LKB1/AAK1 dual inhibitor is an effective inhitor against multi-kinase especially Pim-1 kinase, which has been newly found to highly expressed in sorts of isolated human cancer cells. Kd: 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1.
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Purity:
98%
Appearance:
Powder
Synonyms:
Pim1/AKK1-IN-1; CHEMBL516312; N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide; N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide; Pim1 AKK1-IN-1
Solubility:
10 mM in DMSO
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
LKB1/AAK1 dual inhibitor is an effective inhitor against multi-kinase especially Pim-1 kinase, which has been newly found to highly expressed in sorts of isolated human cancer cells.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
JTSLALYXYSRPGW-UHFFFAOYSA-N
InChI:
InChI=1S/C20H13N5O/c21-9-13-3-5-14(6-4-13)16-8-17-18(12-24-19(17)23-11-16)25-20(26)15-2-1-7-22-10-15/h1-8,10-12H,(H,23,24)(H,25,26)
Canonical SMILES:
C1=CC(=CN=C1)C(=O)NC2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)C#N
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