Liothyronine Sodium - CAS 55-06-1
Catalog number: 55-06-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C15H12I3NO4.Na
Molecular Weight:
672.96
COA:
Inquire
Targets:
Others
Description:
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
Purity:
>98%
MSDS:
Inquire
InChIKey:
SBXXSUDPJJJJLC-YDALLXLXSA-M
InChI:
InChI=1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
Canonical SMILES:
C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)[O-])N)I)I)O.[Na+]
1.Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts.
He B1, Wang M1, Guo H1, Jia Y1, Yang X1, Zhao R1. Animal. 2016 Apr 4:1-6. [Epub ahead of print]
Nutrients are essential for the health and survival of human beings and animals. Also, they play a major role in enhancing reproductive efficiency. The aim of the current study was to investigate the effects of sodium butyrate (SB) on reproductive performance and colostrum composition in gilts. A total of 40 Large White×Landrace replacement gilts (at the age of 160 to 175 days) were fed either a standard diet (control group, n=20) or standard diet top dressed with encapsulated SB at the level of 500 mg/kg (SB group, n=20) from 1 month before mating to 7 days after farrowing. The rate of gilts regular return to estrus after insemination was lower in SB group than the control group. The total number of piglets born (P=0.179) and the litter weight at birth (P=0.063) did not differ between the two treatment groups. However, the mean BW at day 7 tended to be greater in SB group (P=0.051) and average daily gain of piglets was greater (P=0.011) compared with control group.
2.Effects of different dl-selenomethionine and sodium selenite levels on growth performance, immune functions and serum thyroid hormones concentrations in broilers.
Wang Y1, Wang H1, Zhan X1,2. J Anim Physiol Anim Nutr (Berl). 2015 Nov 26. doi: 10.1111/jpn.12396. [Epub ahead of print]
This trial was conducted in a 2 × 3 + 1 factorial arrangement based on a completely randomized design to evaluate the effects of different dl-selenomethionine (dl-Se-Met) and sodium selenite (SS) levels on growth performance, immune functions and serum thyroid hormones concentrations in broilers. A total of 840 Ross 308 broilers (7 days old) were allocated by body weight to seven treatments (three replicates of 40 birds each treatment) including (1) basal diet (containing 0.04 mg of selenium (Se)/kg; control) without supplementary Se; (2, 3 and 4) basal diet + 0.05, 0.15 or 0.25 mg/kg Se as SS; (5, 6 and 7) basal diet + 0.05, 0.15 or 0.25 mg/kg Se as dl-Se-Met. The experiment lasted 42 days. The results revealed that dietary Se supplementation improved (p < 0.05) average daily gain, feed efficiency, immune organ index, serum immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM) and triiodothyronine (T3 ) concentrations and decreased (p < 0.
3.[Association of serum free triiodothyronine with long-term outcome in heart failure patients receiving cardiac resynchronization therapy].
Mi J1, Liu Z, Yang S, Hua W, Chen K, Ding L, Zhang S. Zhonghua Yi Xue Za Zhi. 2015 Dec 19;95(48):3903-7. doi: 10.3760/cma.j.issn.0376-2491.2015.48.006.
OBJECTIVE: To explore the prognostic role of free triiodothyronine (FT3) on all-cause mortality and heart failure (HF) hospitalization in patients receiving cardiac resynchronization therapy (CRT).
4.Antioxidant Potential of Spirulina platensis Mitigates Oxidative Stress and Reprotoxicity Induced by Sodium Arsenite in Male Rats.
Bashandy SA1, El Awdan SA1, Ebaid H2, Alhazza IM3. Oxid Med Cell Longev. 2016;2016:7174351. doi: 10.1155/2016/7174351. Epub 2016 Jan 13.
The present study aimed to examine the protective role of Spirulina platensis (S. platensis) against arsenic-induced testicular oxidative damage in rats. Arsenic (in the form of NaAsO2 at a dose of 6.3 mg/kg body weight for 8 weeks) caused a significant accumulation of arsenic in testicular tissues as well as a decrease in the levels of testicular superoxide dismutase (SOD), catalase (CAT), reduced glutathione, and zinc. Moreover, it significantly decreased plasma testosterone, luteinizing hormone (LH), triiodothyronine (T3), and thyroxine (T4) levels and reduced sperm motility and sperm count. Arsenic (AS) led to a significant increase in testicular malondialdehyde (MDA), tumour necrosis factor alpha (TNF-α), nitric oxide (NO), and sperm abnormalities. S. platensis at a dose of 300 mg/kg was found to attenuate As-induced oxidative stress, testicular damage, and sperm abnormalities by its potent antioxidant activity. S. platensis may represent a potential therapeutic option to protect the testicular tissue from arsenic intoxication.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 53501-41-0 PIT 1

PIT 1
(CAS: 53501-41-0)

PIT 1 is an apoptosis inducing selective PIP3 antagonist which has been shown to inhibit the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50...

CAS 141400-58-0 PX-12

PX-12
(CAS: 141400-58-0)

PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated ...

CAS 1646-88-4 Aldicarb sulfone

Aldicarb sulfone
(CAS: 1646-88-4)

Aldicarb Sulfone is an analog of Aldicarb detected in agricultural products as pesticide residue.

CAS 2901-75-9 N-Acetyl-DL-phenylalanine

N-Acetyl-DL-phenylalanine
(CAS: 2901-75-9)

N-Acetyl-DL-phenylalanine is a drug to treat depression.

CAS 479-92-5 Isopropylantipyrinum

Isopropylantipyrinum
(CAS: 479-92-5)

Isopropylantipyrinum is a derivative of phenazone with similar analgesic and antipyretic effects.

CAS 223445-75-8 Atagabalin

Atagabalin
(CAS: 223445-75-8)

Atagabalin, also referred to PD-0200,390, is a gabamimetic agent developed as a treatment for insomnia but was discontinued following unsatisfactory trial resul...

CAS 479203-71-9 HMR 1031

HMR 1031
(CAS: 479203-71-9)

HMR 1031 is a potent and specific integrin α4β1 or very late antigen 4 (VLA-4) receptor antagonist binding to vascular cell adhesion molecule-1 (VCAM-1) and fib...

QL9

QL9 (QLSPFPFDL), derived from the enzyme 2-oxoglutarate dehydrogenase, is a high-affinity alloantigen for the 2C T cell receptor (TCR).

CAS 261365-11-1 MB05032

MB05032
(CAS: 261365-11-1)

MB05032 inhibits human liver FBPase with a potency (IC50 = 16 ± 1.5 nM) significantly greater than the natural inhibitor, AMP (IC50 = 1 μM), and the most well c...

CAS 83-12-5 Phenindione

Phenindione
(CAS: 83-12-5)

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

CAS 501104-16-1 Lalistat 1

Lalistat 1
(CAS: 501104-16-1)

Lalistat 1 is a lysosomal acid lipase inhibitor with IC50 value of 68 nM. It can block LAL-mediated lipid hydrolysis of acetylated LDL and reduce efflux of chol...

CAS 630-56-8 17α-Hydroxyprogesterone Caproate

17α-Hydroxyprogesterone Caproate
(CAS: 630-56-8)

17α-Hydroxyprogesterone Caproate , a synthetic steroidal progestin, is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid used in the treat...

CAS 1507367-00-1 NCL 00017509

NCL 00017509
(CAS: 1507367-00-1)

NCL00017509 is a NIMA related kinase 2 inhibitor with IC50 value of 56 nM. It can induce increased mitotic abnormalities and mitotic delay.

CEP dipeptide 1
(CAS: 816432-15-2)

CEP dipeptide 1 is a CEP dipeptide which has potent angiogenic activity. It is used as mediators of age-related macular degeneration (AMD).

Ono-1082
(CAS: 111111-04-7)

Ono-1082 increases cAMP levels in hepatocytes in rats.

CAS 58-86-6 Xylose

Xylose
(CAS: 58-86-6)

D-Xylose, a natural product, is used in diagnostic malabsorption tests as well as in the production of Furfural.

CAS 112111-45-2 (R)-(-)-Modafinic acid

(R)-(-)-Modafinic acid
(CAS: 112111-45-2)

(R)-(-)-Modafinic acid(Armodafinic acid) is the major metabolite of Modafinil(HY-10521A), which is a central nervous system vigilance promoting agent, which pos...

MS049 oxalate salt

MS049 oxalate salt is a potent and selective PRMT4 and PRMT6 inhibitor. MS049 has been shown to reduce the H3R2me2a mark in HEK293 cells with an IC50 value of 0...

CAS 153381-68-1 7-Epi-docetaxel

7-Epi-docetaxel
(CAS: 153381-68-1)

An isomer of Docetaxel (D494420). Docetaxel injection impurity C.

CAS 2076-91-7 TPT-260 2HCl

TPT-260 2HCl
(CAS: 2076-91-7)

TPT-260 2HCl is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation.

Chemical Structure

CAS 55-06-1 Liothyronine Sodium

Quick Inquiry

Verification code

Featured Items