Linaprazan mesylate - CAS 855998-67-3
Catalog number:
855998-67-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H30N4O5S
Molecular Weight:
462.57
COA:
Inquire
Targets:
H+,K+-ATPase
Description:
Linaprazan can inhibit gastric H(+),K(+)-ATPase activity (IC 50: 1.0 ± 0.2 μM) and acid formation in vitro. Phase II clinical trials for the treatment of Gastroesophageal reflux disease (GERD) were discontinued.
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Purity:
98%
Appearance:
Powder
Synonyms:
AR-h044277AW; AZD-0865 mesilate; AZD-0865 mesylate; Linaprazan mesilate; 8-((2,6-dimethylbenzyl)amino)-N-(2-hydroxyethyl)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide methanesulfonate;248919-64-4(base)
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
Gastroesophageal reflux disease (GERD)
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
QCHUWMQLRFKFDK-UHFFFAOYSA-N
InChI:
1S/C21H26N4O2.CH4O3S/c1-13-6-5-7-14(2)18(13)11-23-19-10-17(21(27)22-8-9-26)12-25-16(4)15(3)24-20(19)25;1-5(2,3)4/h5-7,10,12,23,26H,8-9,11H2,1-4H3,(H,22,27);1H3,(H,2,3,4)
Canonical SMILES:
Cc1cccc(c1CNc2cc(cn3c2nc(c3C)C)C(=O)NCCO)C.CS(=O)(=O)O
Current Developer:
Originator AstraZeneca
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