|Description||Ligustrazine Hydrochloride is a natural product extracted from the rhizomes of Ligusticum chuanxiong Hort. It displayed a protection effect on injured ECV304 cells in vitro. It also has certain protection effect on the vascular endothelium undergoing CPB, and lower excessive activation of coagulation reaction and inflammation reaction in patients undergoing CPB.|
|Synonyms||2,3,5,6-Tetramethylpyrazine hydrochloride;Chuanxiongzine Hydrochlorid;Tetramethylpyrazine hydrochloride;Ligustrazine HCl|
|Solubility||10 mM in DMSO|
|Application||Ligustrazine Hydrochloride displayed a protection effect on injured ECV304 cells in vitro. It also has certain protection effect on the vascular endothelium undergoing CPB, and lower excessive activation of coagulation reaction and inflammation reaction in patients undergoing CPB.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Quantity||Grams to Kilograms|
A tetracyclic diterpenoid with a beyerane core has drawn attention because it can exhibit antihypertensive activity, reduce blood glucose, suppress cancer cells...
UNIL088 is a water-soluble prodrug of cyclosporine A (CsA), can be rapidly hydrolysed under physiological conditions, and can retain a long shelf-life in aqueou...
MI-538, a 4-methylpyrazole compound, is a double substituted analogue with methylpyrazole at R1 and hydroxyl at R4. MI-538, a potent and selective MLL (Mixed Li...
ARN-5187, a piperazin derivative, has been found to be a REV-ERBβ inhibitor that could induce apoptotic in cancer cells and probably be more effective in breast...
Folic acid is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, and it also acts as a cofactor in biological reactions involving folate....
Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo.
TC-O9311 is a potent, selective agonist of GPR139 (EC50 = 39 nM in CHO-K1 cells expressing human GPR139) with no activity against a range of 90 diverse targets.
Splenopentin diacetate is a synthetic immunomodulating peptide corresponding to the region 32-34 of a splenic product called splenin (SP) and the thymic hormone...
Berberine chloride hydrate
The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways ...
Fraxinol can be extracted from the bark of Fraxinus chinensis Roxb.
GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit ...
CFI-401980, a pyrazolotriazin derivative, has been found to be a TTK inhibitor that could exhibit good antiproliferative activity in some human cancer cell line...
Arg-Gly-Asp-Cys is the binding motif of fibronectin to cell adhesion molecules, and surfaces modified with RGDC were shown to be effective for osteoblast bindin...
Tocofersolan is a synthetic water-soluble version of vitamin E unlike its natural counterpart which are fat soluble . It is polyethylene glycol derivative of α-...
Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expect...
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain. THK5351 bound to AD hippocampal homogenates with high a...
Aprindine is a Class 1b antiarrhythmic agent as a cardiac depressant used in arrhythmias.
S-adenosyl-l-methionine (SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depres...