|Description||Lidocaine hydrochloride is the first amino amide–type local anesthetic and antiarrhythmic drug, which has anti-inflammatory properties in vitro and in vivo. It was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. It is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide and then subsequently to the inactive glycine xylidide. It is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery.|
|Synonyms||Alpha-(diethylamino)-2',6'-acetoxylidide hydrochloride;2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamidmonohydrochloride;Lignocaine hydrochloride;Xylocaine hydrochloride|
|Solubility||H2O: ＞ 36 mg/mL|
|Application||Lidocaine hydrochloride is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery.|
|Shelf Life||2 month in rt, long time|
|Quantity||Kilogram to ton|
|Boiling Point||350.8 °C at 760 mmHg|
|Melting Point||77-78 °C|
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