Liafensine - CAS 1198790-53-2
Catalog number:
1198790-53-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H22N4
Molecular Weight:
366.47
COA:
Inquire
Targets:
Adrenergic Receptor
Description:
This active molecular is a SNDR (serotonin-norepinephrine-dopamine reuptake) inhibitor It was originated by Bristol-Myers Squibb for the treatment of major depressive disorder. In Feb 2013, Phase-II clinical trials in Major depressive disorder (treatment-experienced) in Argentina was on going. In May 2013, Bristol-Myers Squibb completed a phase II trial in Argentina, Australia, Austria, Canada, France, India, Italy, Puerto Rico, South Africa, Spain, United Kingdom and USA. In Oct 2013, Bristol-Myers Squibb discontinued a phase II trial in Major depressive disorder (treatment resistant) because of its increased capacity for side effects as well as potential for abuse.
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Purity:
98%
Appearance:
Powder
Synonyms:
6-[(4S)-2-methyl-4-naphthalen-2-yl-3,4-dihydro-1H-isoquinolin-7-yl]pyridazin-3-amine;BMS 820836
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
the treatment of major depressive disorder
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
VCIBGDSRPUOBOG-QFIPXVFZSA-N
InChI:
InChI=1S/C24H22N4/c1-28-14-20-13-19(23-10-11-24(25)27-26-23)8-9-21(20)22(15-28)18-7-6-16-4-2-3-5-17(16)12-18/h2-13,22H,14-15H2,1H3,(H2,25,27)/t22-/m0/s1
Canonical SMILES:
CN1CC(C2=C(C1)C=C(C=C2)C3=NN=C(C=C3)N)C4=CC5=CC=CC=C5C=C4
Current Developer:
Originator: Bristol-Myers Squibb
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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