LGD-4665 - CAS 1192571-53-1
Catalog number: 1192571-53-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Description:
LGD-4665, an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies.  Research demonstrated that LGD-4665 was well-tolerated with an excellent safety profile. Multiple phase-II studies in thrombocytopenic patients due to ITP, Hep-C and MDS with daily and weekly dosing regimens, as well as additional Phase-I pharmacology studies in healthy volunteers are underway.
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Synonyms:
LGD-4665.
MSDS:
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Current Developer:
Ligand Pharmaceuticals
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