|Description||This active molecular is a selective ATP-competitive inhibitor of Pan-PIM kinase. LGB-321 is active in PIM2 dependent cell lines that is quite different to other PIM inhibitors reported before. LGB321 inhibits proliferation of a number of cell lines derived from diverse hematological malignancies which is consistent with its activity on all three PIM kinases. LGB321 is efficient in inhibiting tumor xenografts and is well-tolerated within the therapeutic exposure range in animal models.|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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