Lexibulin dihydrochloride - CAS 917111-49-0
Catalog number: 917111-49-0
Category: Inhibitor
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Molecular Formula:
C24H32Cl2N6O2
Molecular Weight:
507.46
COA:
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Targets:
Microtubule/Tubulin
Description:
Lexibulin dihydrochloride is an orally bioavailable small-molecule with tubulin-inhibiting, vascular-disrupting, and potential antineoplastic activities. It inhibits tubulin polymerization in tumor blood vessel endothelial cells and tumor cells, blocking the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase, which may result in disruption of the tumor vasculature and tumor blood flow, and tumor cell death.
Purity:
>98%
Synonyms:
CYT-997 dihydrochloride; CYT 997 dihydrochloride; CYT997 dihydrochloride
MSDS:
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InChIKey:
HGDCRTLMRFHNOZ-TXEPZDRESA-N
InChI:
InChI=1S/C24H30N6O2.2ClH/c1-5-8-19(18-9-7-12-25-15-18)28-22-16(3)14-27-23(30-22)17-10-11-20(21(13-17)32-4)29-24(31)26-6-2;;/h7,9-15,19H,5-6,8H2,1-4H3,(H2,26,29,31)(H,27,28,30);2*1H/t19-;;/m0../s1
Canonical SMILES:
CCCC(C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC.Cl.Cl
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CAS 917111-49-0 Lexibulin dihydrochloride

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