|Description||Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.Levosulpiride is used in the treatment of psychoses, particularly negative symptoms of schizophrenia, anxiety disorders, dysthymia, vertigo, dyspepsia, irritable bowel syndrome and premature ejaculation.|
N 0734 hydrochloride
N 0734 hydrochloride is a potent and selective dopamine (DA) receptor agonist.
Metoclopramide hydrochloride hydrate
Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist used to treat nausea and vomitin.
Prop-2-ynyl-2-Aminotetraline hydrochloride is a dopamine receptor agonist.
RO10-5824 is a D4-selective partial agonist (EC50 = 205 nM) that binds with high affinity (Ki = 5.2 nM), and is approximately 250-fold selectivity over D3 recep...
Fananserin is a 5-HT2A receptor and a dopamine D4 receptor antagonist (Ki = 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT2A, D4, H1, α1, 5-HT1A and D2 receptors, r...
Ziprasidone hydrochloride monohydrate
The hydrochloride monohydrate salt form of Ziprasidone, a benzothiazol derivative, has been found to be a 5HT2A and D2 receptor antagonist that could be used ag...
A dopamine receptor agonist.
SKF 38393 hydrobromide
SKF 38393 hydrobromide is a selective dopamine D1-like receptor partial agonist (Ki = 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors,...
Thioridazine hydrochloride is a dopamine receptor antagonist displaying antipsychotic activity. Thioridazine induces apoptosis via targeting the PI 3-K/Akt/mTOR...
Lisuride maleate, an ergot derivative, is a nonselective dopamine receptor agonist with high affinity for D2, D3 and D4 receptors along with 5-HT1A. As an anti-...
PAOPA is an allosteric modulator of dopamine D2 receptors. It can prevent and reverse behavioral and biochemical abnormalities in an amphetamine-sensitized anim...
NS 30678 hydrochloride
NS 30678 hydrochloride is a dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki = 9.7 nM, IC50 = 7 nM, in HEK-hD2L-Gαqi5...
Domperidone is a medication developed by Janssen Pharmaceutica that acts as a peripherally-selective antagonist of the dopamine D2 and D3 receptors.
Fenoldopam is a selective D1 receptor partial agonist, binds to α2-adrenoceptors, increasing renal blood flow used as an antihypertensive agent.
Fluspirilene, with antipsychotic activity, is a non-competitive antagonist of agonist-activated L-type calcium channels (IC50 = 0.03 µM). Fluspirilene is also a...
PD-119819, a heterocyclic piperazine, is an extremely selective DA autoreceptor agonist. It binds [3H]haloperidol in tests in rats. It inhibits of spontaneous l...
(+)-PHNO hydrochloride is a potent and selective dopamine D2 agonist.
Etybenzatropine is an anticholinergic/antihistamine. It is used as an antiparkinsonian agent. It may act as a dopamine reuptake inhibitor.
Flupenthixol dihydrochloride is a dopamine receptor antagonist used as an antipsychotic drug for schizophrenia treatment. Mixture of E/Z isomers (ratio: 60:40).
A dopamine receptor agonist.